1. Delftia Acidovorans pneumonia with lung cavities formation
- Author
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Yildiz, Hanifi, Sünnetçioğlu, Aysel, Ekin, Selami, Baran, Ali İrfan, Özgökçe, Mesut, Aşker, Selvi, Üney, İbrahim, Turgut, Engin, and Akyüz, Sümeyye
- Subjects
medicine.medical_specialty ,pneumonia por bacterias ,Delftia acidovorans ,Case Report ,respiratory tract infections ,tos ,multiple pulmonary nodules ,03 medical and health sciences ,bacterial pneumonia ,infecciones del tracto respiratorio ,cough ,medicine ,huesped immunocomprometido ,piperacilina ,gram-negative bacterial infections ,immunocompromised host ,Piperacillin ,lung diseases interstitial ,Multiple Pulmonary Nodules ,030505 public health ,Lung ,biology ,business.industry ,infecciones bacteria gram-negativas ,Cavitary pneumonia ,Bacterial pneumonia ,General Medicine ,medicine.disease ,biology.organism_classification ,respiratory sounds ,Pneumonia ,medicine.anatomical_structure ,Delftia ,enfermedad pulmonar intersticial ,Piperacillin Tazobactam drug combination ,nódulos múltiples pulmonares ,Sputum ,sonidos respiratorios ,Radiology ,medicine.symptom ,0305 other medical science ,business ,combinación de medicamentos piperailina-tazobactam - Abstract
Case Description: A 52-year-old female patient was admitted to our clinic with complaints of cough, sputum, fever and fatigue. The patient has been receiving immunosuppressive therapy for thrombocytopenic purpura for 5 years. Clinical Finding: Inspiratory crackles were heard on both hemithorax. Oxygen saturation measured with the pulse oximeter was 97%. Chest X-ray showed diffuse reticular opacities that were more prominent in the upper zones of both lungs. WBC counts were 17600/mm3 and Platelet counts were 29000/mm3. Thorax CT showed that there were many thin-walled cavities and millimetric nodules accompanied by ground-glass infiltrates in the upper and middle lobes. Gram staining of bronchial fluid, taken by bronchoscopy, revealed Gram-negative bacilli and intense polymorphonuclear leukocytes. The bacteria were defined as Delftia acidovorans by BD Phoenix automated system. Treatment and outcomes: The patient was hospitalized with suspicion of opportunistic pulmonary infections and cavitary lung disease. After the empirical treatment of intravenous piperacillin-tazobactam and oral clarithromycin, her clinical and radiological findings significantly regressed, and she was discharged with outpatient follow-up. Clinical Relevance: This is the first example of cavitary pneumonia due to Delftia acidovorans in an immunocompromised patient. We would like to emphasize that Delftia pneumonia should be considered in the differential diagnosis of pulmonary cavitary involvement in such patients.
- Published
- 2020
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