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14 results on '"C. Fania"'

1. Monoclonal free light chain detection and quantification: Performances and limits of available laboratory assays

Author

C. Fania, Paolo Brambilla, Cecilia Sarto, Valerio Leoni, Rinaldo Brivio, Jari Intra, Sarto, C, Intra, J, Fania, C, Brivio, R, Brambilla, P, and Leoni, V

Subjects
030213 general clinical medicine, Laboratory method, Computer science, Clinical Biochemistry, Paraproteinemias, 030204 cardiovascular system & hematology, Immunoglobulin light chain, Mass Spectrometry, 03 medical and health sciences, 0302 clinical medicine, Electrophoresi, medicine, Humans, Immunoassay, Laboratory methods, Chromatography, Monoclonal gammopathy, Free light chain, General Medicine, Clinical Laboratory Services, Free Light Chain, Monoclonal, Biological Assay, Immunoglobulin Light Chains, medicine.symptom, Bence Jones Protein
Abstract

The detection and quantification of immunoglobulin free light chains in serum and urine is recommended for the diagnosis and monitoring of monoclonal gammopathies according to the guidelines of the International Myeloma Working Group (IMWG). Several tests are currently available in the clinical laboratory to detect and quantify free light chains but although quality, efficiency, and effectiveness have been improved, the results are still variable and poorly harmonized and standardized. The present review article wants to analyze these aspects, with a keen eye on techniques, such as mass spectrometry, that could replace in the practical clinical laboratory the current methods including Bence-Jones protein assay and free light chain immunoassays.

Published
2021

2. Validation of the Hingmed WBP-02A device for ambulatory blood pressure monitoring according to the European Society of Hypertension International Protocol revision 2010

Author

Leonardo Vezzù, Ilaria Lazzaretto, C. Fania, and Paolo Palatini

Subjects
Male, medicine.medical_specialty, Ambulatory blood pressure, Systole, Adult population, Diastole, Blood Pressure, 030204 cardiovascular system & hematology, Assessment and Diagnosis, International Protocol of the European Society of Hypertension (ESH-IP), 03 medical and health sciences, DEVICE EVALUATION, 0302 clinical medicine, Internal medicine, ambulatory blood pressure (BP) monitoring, Hingmed, International Protocol of the European Society of Hypertension (ESH-IP), Internal Medicine, medicine, Humans, 030212 general & internal medicine, Aged, Advanced and Specialized Nursing, Protocol (science), Aged, 80 and over, business.industry, General Medicine, Blood Pressure Monitoring, Ambulatory, Middle Aged, Circumference, Blood Pressure Monitors, Blood pressure, Hypertension, Cardiology, ambulatory blood pressure (BP) monitoring, Hingmed, Female, Cardiology and Cardiovascular Medicine, business
Abstract

The objective of this study was to determine the accuracy of the Hingmed WBP-02A device for ambulatory blood pressure (BP) monitoring according to the International Protocol of the European Society of Hypertension (ESH-IP). Device evaluation was carried out in 33 patients. The mean age was 69.8±13.8 years, the mean systolic BP was 137.6±27.0 mmHg (range: 96-172), the mean diastolic BP was 86.7±20.1 mmHg (range: 48-124) and the mean arm circumference was 30.1±6.2 cm (range: 20-43). The protocol requirements were followed precisely. Four different cuffs, small, standard, large, and extra-large were used. The device comfortably passed all ESH-IP requirements, as 84 out of 99 device-observer systolic BP differences and 97 of 99 diastolic BP differences were within ±5 mmHg thereby fulfilling the standards of the protocol. Device-observer BP differences were unrelated to arm circumference. These data show that the Hingmed WBP-02A device for ambulatory BP monitoring met the requirements for validation by the ESH-IP and can be recommended for clinical use in the adult population.

Published
2019

3. ELEVATED PULSE PRESSURE IN HYPERTENSION OF THE YOUNG

Author

P. Palatini, G. Garavelli, Edoardo Casiglia, A. Mazzer, Francesca Saladini, L. Mos, Paolo Spinella, C. Fania, and G. Zanata

Subjects
medicine.medical_specialty, Increased risk, Physiology, business.industry, Internal medicine, Internal Medicine, Cardiology, Medicine, Hemodynamics, Disease, Cardiology and Cardiovascular Medicine, business, Pulse pressure
Abstract

Objective:The prognostic significance of elevated pulse pressure (PP) in the young is still a matter for debate. Previous studies suggest that high PP carries an increased risk of cardiovascular disease in women but not in men. We aimed to identify clinical, metabolic and haemodynamic characteristic

Published
2019

4. [PP.09.19] LONG-TERM WELL-CONTROLLED BLOOD PRESSURE LEVELS AND CAROTID ELASTICITY IN YOUNG HYPERTENSIVE SUBJECTS

Author

Paolo Palatini, C. Fania, Massimo Puato, Paolo Pauletto, Raffaele Pesavento, and Marcello Rattazzi

Subjects
Ldl cholesterol, medicine.medical_specialty, hypertension, Physiology, business.industry, vascular compliance, medicine.disease, Arterial stiffness, Vascular compliance, Blood pressure, BP, carotid intima-media thickness (IMT), Internal medicine, Arterial stiffness, hypertension, carotid distensibility, vascular compliance, carotid intima-media thickness (IMT), BP, LDL-cholesterol, Internal Medicine, Cardiology, medicine, LDL-cholesterol, Elasticity (economics), Cardiology and Cardiovascular Medicine, business, carotid distensibility
Published
2017

5. RECTANGULAR CUFFS OVERESTIMATE BLOOD PRESSURE IN OBESE PEOPLE WITH VERY LARGE ARMS

Author

P. Palatini, C. Fania, Elisabetta Benetti, and Francesca Saladini

Subjects
medicine.medical_specialty, Physiology, business.industry, Hypertension, Cuffs, Tronco-conical, Blood pressure, Obese people, Obesity, Upper arm shape, Upper arm shape, Cuffs, Blood pressure, Internal medicine, Hypertension, Internal Medicine, Cardiology, Medicine, Tronco-conical, Obesity, Obese people, Cardiology and Cardiovascular Medicine, business
Published
2018

6. ARM SIZE AND DISTAL UPPER ARM SLANT ANGLE PREDICT THE MEASUREMENT ERROR WITH RECTANGULAR CUFFS IN THE OBESE

Author

Paolo Spinella, C. Fania, Elisabetta Benetti, G. D’Amico, Francesca Saladini, P. Palatini, F. Gasparotti, Andrea Ermolao, Edoardo Casiglia, and Andrea Gasperetti

Subjects
Blood pressure, Observational error, Physiology, business.industry, Slant angle, Internal Medicine, Medicine, Cardiology and Cardiovascular Medicine, business, Biomedical engineering
Abstract

Objective:Published evidence has shown that tronco-conical cuffs and bladders should be used for accurate blood pressure (BP) measurement in the obese. Not only arm size but also its shape may affect the accuracy of BP measurement. Aim of this study was to investigate the arm characteristics that ca

Published
2019

8. [OP.3C.08] ELEVATED PULSE PRESSURE IN YOUNG TO MIDDLE AGE MEN CARRIES A REDUCED RISK OF ADVERSE OUTCOME

Author

A. Bortolazzi, Paolo Palatini, G. Garavelli, C. Fania, A. Mazzer, L. Mos, Francesca Saladini, and Edoardo Casiglia

Subjects
Reduced risk, medicine.medical_specialty, Physiology, Adverse outcomes, business.industry, medicine.disease, Middle age, Pulse pressure, Emergency medicine, Internal Medicine, medicine, Medical emergency, Cardiology and Cardiovascular Medicine, business
Published
2017

9. [BP.11.05] URIC ACID AND HYPERTENSION. ROLE OF RENIN ANGIOTENSIN AND SYMPATHETIC NERVOUS SYSTEMS ACTIVITY

Author

Francesca Saladini, G. Zanata, G. Garavelli, Paolo Palatini, C. Fania, A. Bortolazzi, Edoardo Casiglia, and L. Mos

Subjects
medicine.medical_specialty, Angiotensin receptor, Angiotensin II receptor type 1, Physiology, business.industry, medicine.disease, chemistry.chemical_compound, Endocrinology, chemistry, Pathophysiology of hypertension, Internal medicine, Renin–angiotensin system, Internal Medicine, Medicine, Uric acid, Cardiology and Cardiovascular Medicine, business
Published
2017

10. RISK OF DEVELOPING SUSTAINED HYPERTENSION IN ISOLATED SYSTOLIC HYPERTENSION OF THE YOUNG IDENTIFIED WITH AMBULATORY BLOOD PRESSURE MONITORING

Author

L. Mos, G. Garavelli, C. Fania, P. Palatini, A. Mazzer, and Francesca Saladini

Subjects
medicine.medical_specialty, Ambulatory blood pressure, Systolic Hypertension, Physiology, business.industry, Young, Hypertension, Sustained Hypetension, Systolic Hypertension, Young, ABPM, Ambulatory Blood Pressure Monitoring, Sustained Hypetension, Internal medicine, Hypertension, Isolated systolic hypertension, ABPM, Internal Medicine, Cardiology, Medicine, Cardiology and Cardiovascular Medicine, business, Ambulatory Blood Pressure Monitoring
Published
2018

11. YOUNG ISOLATED SYSTOLIC HYPERTENSION DIFFER ACCORDING TO THE LEVEL OF PHYSICAL ACTIVITY

Author

A. Mazzer, Paolo Palatini, C. Fania, Edoardo Casiglia, L. Mos, and Francesca Saladini

Subjects
medicine.medical_specialty, Physiology, business.industry, Young, Physical activity, Hyperttension, ISHY, Phisical Activity, Athletes, Internal medicine, Hyperttension, Isolated systolic hypertension, ISHY, Young, Phisical Activity, Athletes, Ambulatory blood pressure monitoring, ABPM, Isolated systolic hypertension, ABPM, Internal Medicine, medicine, Cardiology, Ambulatory blood pressure monitoring, Cardiology and Cardiovascular Medicine, business
Published
2018

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