Search

Your search keyword '"Haruhisa Inoue"' showing total 132 results

Search Constraints

Start Over You searched for: Author "Haruhisa Inoue" Remove constraint Author: "Haruhisa Inoue" Topic medicine Remove constraint Topic: medicine
132 results on '"Haruhisa Inoue"'

Search Results

1. Protocol for a phase 2 study of bosutinib for amyotrophic lateral sclerosis using real-world data: induced pluripotent stem cell-based drug repurposing for amyotrophic lateral sclerosis medicine (iDReAM) study

2. AAV-mediated editing of PMP22 rescues Charcot-Marie-Tooth disease type 1A features in patient-derived iPS Schwann cells

3. Differentiation of human induced pluripotent stem cells into hypothalamic vasopressin neurons with minimal exogenous signals and partial conversion to the naive state

4. Cellular analysis of SOD1 protein-aggregation propensity and toxicity: a case of ALS with slow progression harboring homozygous SOD1-D92G mutation

5. TDP-43 regulates cholesterol biosynthesis by inhibiting sterol regulatory element-binding protein 2

6. Metabolites of soil microorganisms modulate amyloid β production in Alzheimer’s neurons

7. Repurposing bromocriptine for Aβ metabolism in Alzheimer’s disease (REBRAnD) study: randomised placebo-controlled double-blind comparative trial and open-label extension trial to investigate the safety and efficacy of bromocriptine in Alzheimer’s disease with presenilin 1 (PSEN1) mutations

9. TDP-43 stabilises the processing intermediates of mitochondrial transcripts

10. Induced pluripotent stem cell–based Drug Repurposing for Amyotrophic lateral sclerosis Medicine (iDReAM) study: protocol for a phase I dose escalation study of bosutinib for amyotrophic lateral sclerosis patients

11. Anti-Aβ drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer's disease.

12. P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating.

13. Simple derivation of skeletal muscle from human pluripotent stem cells using temperature‐sensitive Sendai virus vector

14. iPSC screening for drug repurposing identifies anti‐RNA virus agents modulating host cell susceptibility

15. Deep Learning and ALS

16. [Recommendations (Proposal) for promoting research for overcoming neurological diseases 2020]

17. From in vitro to in vivo reprogramming for neural transdifferentiation: An approach for CNS tissue remodeling using stem cell technology

18. Galectin 3–binding protein suppresses amyloid-β production by modulating β-cleavage of amyloid precursor protein

19. Human iPS cell-derived mural cells as an in vitro model of hereditary cerebral small vessel disease

20. High molecular weight amyloid β 1‐42 oligomers induce neurotoxicity via plasma membrane damage

21. MiR-33a is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons

22. Human induced pluripotent stem cells generated from a patient with idiopathic basal ganglia calcification

23. microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity

24. Generation of Motor Neurons from Human ESCs/iPSCs Using Sendai Virus Vectors

25. Induction of inverted morphology in brain organoids by vertical-mixing bioreactors

26. High molecular weight amyloid β 1‐42 oligomers induce neurotoxicity via plasma membrane damage

27. Nasal vaccine delivery attenuates brain pathology and cognitive impairment in tauopathy model mice

28. Generation of a human induced pluripotent stem cell line derived from a Parkinson's disease patient carrying SNCA duplication

29. Generation of a human induced pluripotent stem cell line, BRCi004-A, derived from a patient with age-related macular degeneration

30. ALS, a cellular whodunit on motor neuron degeneration

31. Evaluation of Toxic Amyloid β42 Oligomers in Rat Primary Cerebral Cortex Cells and Human iPS-derived Neurons Treated with 10-Me-Aplog-1, a New PKC Activator

32. Overexpressed wild-type superoxide dismutase 1 exhibits amyotrophic lateral sclerosis-related misfolded conformation in induced pluripotent stem cell-derived spinal motor neurons

33. A phase I dose escalation study of bosutinib for amyotrophic lateral sclerosis: Induced pluripotent stem cell-based drug repurposing for amyotrophic lateral sclerosis medicine (IDREAM) study

34. iPSC-Based Compound Screening and InVitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer’s Disease

35. Induced pluripotent stem cells derived from a patient with familial idiopathic basal ganglia calcification (IBGC) caused by a mutation in SLC20A2 gene

36. Induced pluripotent stem cells derived from an autosomal dominant lateral temporal epilepsy (ADLTE) patient carrying S473L mutation in leucine-rich glioma inactivated 1 ( LGI1 )

37. Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice

38. A simplified and sensitive method to identify Alzheimer’s disease biomarker candidates using patient-derived induced pluripotent stem cells (iPSCs)

39. Antisense Oligonucleotides Reduce RNA Foci in Spinocerebellar Ataxia 36 Patient iPSCs

40. Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model

41. In Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling

42. Induced pluripotent stem cell-based Drug Repurposing for Amyotrophic lateral sclerosis Medicine (iDReAM) study: protocol for a phase I dose escalation study of bosutinib for amyotrophic lateral sclerosis patients

43. Brief review: Can modulating DNA methylation state help the clinical application of oligodendrocyte precursor cells as a source of stem cell therapy?

44. Functional evaluation of PDGFB-variants in idiopathic basal ganglia calcification, using patient-derived iPS cells

45. Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I

46. DNA damage in embryonic neural stem cell determines FTLDs’ fate via early-stage neuronal necrosis

47. Multimodal Imaging for DREADD-Expressing Neurons in Living Brain and Their Application to Implantation of iPSC-Derived Neural Progenitors

48. Cytoplasmic aggregates of dynactin in iPSC-derived tyrosine hydroxylase-positive neurons from a patient with Perry syndrome

49. Generation of a human induced pluripotent stem cell line, BRCi009-A, derived from a patient with glycogen storage disease type 1a

50. Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development

Catalog

Books, media, physical & digital resources