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In this paper, the shear wrinkles of a rectangular membrane under the pretension were analyzed firstly. A critical shear distance was then obtained based on the tension field theory. An expression between the wavelength and the amplitude of the membrane wrinkles were developed using the Von Karman large deflection formula. The simulation flow of the membrane wrinkles were also established using the nonlinear post-buckling analytical method. The results indicated that the wrinkle was firstly generated on both sides of the membrane and then extended to the center. The wrinkle amplitude increased with the shear distance increases. The wrinkle formation and expansion were effectively resisted by increasing the initial pretension. Buckling mode of the shear membrane was unstable in the post-buckling process and the secondary buckling phenomenon was obviously observed. The theoretical and numerical results were compared to verify the rationality of the theoretical and simulation results.

The medial olivocochlear reflex (MOCR) is known to affect cochlear signal processing via the electromechanical changes it induces in outer hair cells (OHCs). Experiments showed that electrically stimulating the MOC efferents (i.e., open-loop stimulation) suppresses cochlear responses to acoustic noise while enhancing the response to tone bursts if the signal-to-noise ratio is sufficiently high [5]. However, such experiments did not reveal precisely how MOCR affects cochlear signal processing in a close loop. Presently we have built an integrated computer model for the MOCR pathway; the constituting sub-models include a model for cochlear mechanics with electromotile OHCs [11], a neurotransmitter release model for the synapse between inner hair cells (IHCs) and spiral ganglion cells [16], an electrical model for the T-multipolar (TM) cells in the cochlear nucleus [6], a relay from TM cells to the MOC interneurons, and a convolution kernel describing the change of OHC potassium conductance triggered by the ...

Objectives Women and men have been shown to have different prevalence, clinical presentations, and outcomes of coronary artery disease. It is unclear whether atheroma burden and characteristics of coronary plaques differ between genders. Methods We performed IVUS assessments in 81 patients with ACS. IVUS analysis included qualitative and quantitative measurements. Clinical parameters and coronary imaging parameters obtained by IVUS were compared between men and women. Results Men had more smoking than women (80% vs 4.8%, P 2 ), external elastic membrane (13.73 ± 5.00 vs 15.28 ± 6.53mm 2 ), plaque area (10.27 ± 4.86 vs 12.01 ± 5.21mm 2 ), and plaque burden (0.73 ± 0.11 vs 0.81 ± 0.11) were not significantly different between men and women. Women had less plaque rupture compared with men (23.8% vs 51.7%, P Conclusions Men and women had similar plaque burden, and women had less plaque rupture compared with men in ACS patients.

Objective To observe the safety and efficiency of utilisation of ZEEK thrombus aspiration catheters in patients who recovering from acute myocardial infarction (AMI) underwent elective percutaneous coronary intervention (PCI). Methods From July 2007 to December 2009, 61 patients with recovering from AMI (41 males, mean age of 59.27±10.56 years) were randomly received utilisation of ZEEK thrombus aspiration catheter (aspiration group, n=31) or routine PCI (non-aspiration group, n=30). Clinical and angiographic features between the two groups were analysed. Results Baseline clinical features were similar between the two groups. TIMI 3 flow rate (93.55% vs 56.67%, p=0.001) immediately after PCI was significantly higher in aspiration group than that in non-aspiration group. Slow flow (TIMI 2 flow) rate (6.45% vs 26.66%, p=0.013), no-reflow (TIMI 0–1flow) rate (0 vs 16.67%, p=0.024), and corrected TIMI frames (27.94–5.80 vs 39.20±5.33, p=0.000) immediately after PCI were significantly lower in aspiration group than that in non-aspiration group. Left ventricular ejection fraction (LVEF) ((56.48±9.77)% vs 47.10±9.24)%, p=0.000), the rate of E peak/A peak Conclusions Utilisation of ZEEK thrombus aspiration catheters in patients with recovering from AMI is safe and effective, the thrombus aspiration catheters can effectively remove coronary thrombus, improve myocardial tissue perfusion, and can improve postoperative cardiac function, without increasing major adverse cardiac events.