Search

Your search keyword '"Marcel Neuenhoff"' showing total 3 results
Start Over Author "Marcel Neuenhoff" Topic medicine
3 results on '"Marcel Neuenhoff"'

1. Detection and Characterization of Clinical Bordetella trematum Isolates from Chronic Wounds

Author

Christian Buechler, Claudio Neidhöfer, Thorsten Hornung, Marcel Neuenhoff, and Marijo Parčina

Subjects
Burkholderiales, Alcaligenaceae, Bordetella trematum, non-fermenting Gram-negative bacilli, wound infection, chronic wounds, Medicine
Abstract

Bordetella trematum is a relatively newly discovered and potentially frequently overlooked Bordetella species, mostly isolated from chronic wounds and predominantly in those of the lower extremities. Its susceptibility profile and clinical significance is still debated, given the limited amount of available data. We contribute providing a molecular and phenotypical analysis of three unique clinical B. trematum isolates detected between August 2019 and January 2020 to aid the matter. Cryo-conserved isolates were subcultured and re-identified using various routine means of identification. Bacterial genomes were fully Illumina-sequenced and phenotypical susceptibility was determined by broth microdilution and gradient-strip tests. All isolates displayed increased susceptibility to piperacillin–tazobactam (B. trematum can be resistant to trimethoprim/sulfamethoxazole is warranted.

Published
2021
Full Text
View/download PDF

2. Comparison of Antimicrobial Susceptibility Test Results of Disk Diffusion, Gradient Strip, and Automated Dilution with Broth Microdilution for Piperacillin-Tazobactam

Author

Hyeon-June Kim, Marcel Neuenhoff, Eliane Dibloni, Christian Buechler, and Thomas Gehring

Subjects
Microbiology (medical), Immunology, Antimicrobial susceptibility, Microbial Sensitivity Tests, Microbiology, Sepsis, Gram-Negative Bacteria, polycyclic compounds, medicine, Escherichia coli, Humans, Pharmacology, Chromatography, Chemistry, fungi, Broth microdilution, food and beverages, Reproducibility of Results, bacterial infections and mycoses, Gradient strip, Dilution, Anti-Bacterial Agents, Klebsiella pneumoniae, Piperacillin, Tazobactam Drug Combination, Piperacillin/tazobactam, Pseudomonas aeruginosa, Diffusion gradient, Gram-Negative Bacterial Infections, medicine.drug
Abstract

In the treatment of septic patients, the prediction of a pathogen's susceptibility to piperacillin–tazobactam can be crucial. Commercial tests are available to measure the pathogen's susceptibility...

Published
2021

3. Detection and Characterization of Clinical Bordetella trematum Isolates from Chronic Wounds

Author

Claudio Neidhöfer, Thorsten Hornung, Marcel Neuenhoff, Marijo Parcina, and Christian Buechler

Subjects
0301 basic medicine, Microbiology (medical), Imipenem, Burkholderiales, antibiotic resistance, 030106 microbiology, Fosfomycin, Article, Microbiology, 03 medical and health sciences, 0302 clinical medicine, Alcaligenaceae, Ampicillin, medicine, Immunology and Allergy, 030212 general & internal medicine, diabetic ulcer, Molecular Biology, General Immunology and Microbiology, biology, Sulfamethoxazole, Bordetella trematum, non-fermenting Gram-negative bacilli, wound infection, chronic wounds, Broth microdilution, Sulbactam, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Trimethoprim, Infectious Diseases, Medicine, medicine.drug
Abstract

Bordetella trematum is a relatively newly discovered and potentially frequently overlooked Bordetella species, mostly isolated from chronic wounds and predominantly in those of the lower extremities. Its susceptibility profile and clinical significance is still debated, given the limited amount of available data. We contribute providing a molecular and phenotypical analysis of three unique clinical B. trematum isolates detected between August 2019 and January 2020 to aid the matter. Cryo-conserved isolates were subcultured and re-identified using various routine means of identification. Bacterial genomes were fully Illumina-sequenced and phenotypical susceptibility was determined by broth microdilution and gradient-strip tests. All isolates displayed increased susceptibility to piperacillin–tazobactam (B. trematum can be resistant to trimethoprim/sulfamethoxazole is warranted.

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results