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Rhabdomyolysis is defined as breakdown of skeletal muscle fibers with subsequent release of its cellular components into the circulation. It is associated with variety of causes and status epilepticus is one of it. The excessive muscular activity associated with seizure is possible explanation for it. It is clinically evident by the new onset severe generalized bodyache, weakness and myalgia associated with dark coloured urine. Acute kidney injury is one of the most serious complications associted with rhabdomyolysis. Single episode of generalized seizure is not a frequent cause for rhabdomyolysis. Acute kidney injury due to rhabdomyolysis, following a single episode of seizure is a rare entity. Here we report a case of rhabdomyolysis with acute kidney injury following a single episode of generalized seizure. High index of suspicion is required to timely diagnose and treat such patients. Timely intervention with hemodialysis along with other supportive care can completely revert this potentially serious complication to normal.

A series of experiments were devised to investigate the sequence of events that led to the differentiation of hair cells and their synapses. In particular, we inquired whether the presence of nerve fibers in the developing sense organ is necessary for induction of differentiation. Lateral line organs in the translucent tail of salamander tadpoles (Ambystoma mexicanum) were chosen for this study because here cellular structures can be observed in considerable detail in vivo with interference contrast optics. Furthermore, during degeneration of a new tail after amputation, new neuromasts develop and can be taken for electron microscopy at desired stages of development. At the first identified stage, nerve terminals are already present above the basement membrane. A cupula, afferent synapses, kinocilia, and stereocilia then appear. In another set of experiments, the tail was amputated and at the same time a segment of the lateral line nerve which innervates these organs was surgically removed behind the fron...