10 results on '"S. W. Xu"'
Search Results
2. Dietary taurine supplementation enhances antioxidative capacity and improves breast meat quality of broiler chickens
- Author
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Tong Xing, Feng Gao, Jiaolong Li, L. L. Zhang, Bingbing Ma, Y. Jiang, Zhuang Lu, and S W Xu
- Subjects
Taurine ,Antioxidant ,Meat ,medicine.medical_treatment ,Antioxidants ,Superoxide dismutase ,chemistry.chemical_compound ,medicine ,Animals ,Food science ,Muscle, Skeletal ,biology ,Superoxide ,Broiler ,General Medicine ,Glutathione ,Malondialdehyde ,Animal Feed ,Diet ,chemistry ,Catalase ,Dietary Supplements ,biology.protein ,Animal Science and Zoology ,Chickens ,Food Science - Abstract
1. The aim of this study was to determine the effect of dietary taurine supplementation on growth performance, meat quality and antioxidant responses in breast muscle of broiler chickens.2. A total of 72 Arbor Acres broiler chickens (28-day-old) with similar body weight were randomly allocated into two groups, and fed either 0 g/kg (control; C) or 5 g/kg taurine-supplemented diets (TS) for 14 days.3. The results showed that TS had no effect on growth performance or chemical composition of breast muscle in broilers. The drip and cooking losses were significantly decreased (P < 0.05), and the pH24h of breast muscle were increased (P < 0.05) in the TS group. Meanwhile, broilers in the TS group exhibited significantly higher (P < 0.05) scavenging activities of superoxide and 2,2-diphenyl-1-picrylhydrazyl radicals, and lower (P < 0.05) contents of carbonyl, malondialdehyde, and 4-hydroxynonenal. TS increased (P < 0.05) total antioxidant capacity and superoxide dismutase activities. Moreover, TS significantly upregulated (P < 0.05) the mRNA expressions of nuclear factor erythroid 2-related factor 2 (Nrf2), heme oxygenase 1, NAD(P)H quinone dehydrogenase 1, superoxide dismutase, catalase, and glutathione peroxidase.4. These findings suggested that TS enhanced antioxidative capacity and improved breast meat quality of broilers via activating the Nrf2 pathway.
- Published
- 2019
3. Publisher's Note: Elastic scattering of the proton drip-line nucleus8B off anatPb target at 170.3 MeV [Phys. Rev. C87, 044613 (2013)]
- Author
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R. Wada, S. W. Xu, S. Z. Chen, X. H. Yuan, X. Y. Zhang, Y. Li, L. Jin, Q. Y. Lin, Yi Zhang, Jifeng Hu, F. Fu, G. F. Xu, Xiang Zhang, Wei Zhang, S. Jin, Lin Zhang, X. Xu, Haoxing Xu, Mei-Rong Huang, X. G. Lei, P. Ma, S. L. Li, Z. Q. Chen, X. G. Cao, Q. Wang, S. W. Tang, G. Q. Xiao, C. M. Du, C. Zhen, Z. G. Hu, J. L. Han, Z. Y. Sun, Z. Y. Guo, B. X. Gou, R. F. Chen, N. Keeley, Zhong Chen, J. J. He, F. D. Shi, L. M. Duan, Swagata Mukherjee, Y. Y. Yang, Q. Hu, Z. G. Xu, Minggang Zhao, J. S. Wang, Dan-Yang Pang, J. B. Chen, K. Rusek, L. X. Liu, Z. Bai, and J. B. Ma
- Subjects
Physics ,Elastic scattering ,Nuclear physics ,Nuclear and High Energy Physics ,medicine.anatomical_structure ,Proton ,Nat ,medicine ,Nucleus ,Line (formation) - Published
- 2013
4. Elastic scattering of the proton drip-line nucleus8B off anatPb target at 170.3 MeV
- Author
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L. M. Duan, Swagata Mukherjee, Mei-Rong Huang, J. B. Ma, Q. Hu, Z. Bai, N. Keeley, Zhong Chen, G. Q. Xiao, Q. Wang, C. Zhen, Minggang Zhao, Z. Y. Sun, S. W. Tang, Z. Y. Guo, R. Wada, J. L. Han, G. F. Xu, B. X. Gou, S. Jin, F. D. Shi, Yi Zhang, Y. Li, J. J. He, X. Xu, C. M. Du, X. H. Yuan, X. Y. Zhang, Haoxing Xu, X. G. Cao, Q. Y. Lin, Z. G. Hu, Xiang Zhang, J. S. Wang, S. L. Li, Z. G. Xu, Jifeng Hu, Z. Q. Chen, S. Z. Chen, R. F. Chen, J. B. Chen, K. Rusek, L. X. Liu, X. G. Lei, F. Fu, Y. Y. Yang, Wei Zhang, S. W. Xu, Lin Zhang, P. Ma, Dan-Yang Pang, and L. Jin
- Subjects
Physics ,Elastic scattering ,Nuclear and High Energy Physics ,Discretization ,Scattering ,Coulomb barrier ,Small-angle neutron scattering ,medicine.anatomical_structure ,medicine ,Neutron ,Halo ,Atomic physics ,Nuclear Experiment ,Nucleus - Abstract
The elastic scattering of ${}^{8}$B by a ${}^{\mathrm{nat}}$Pb target was measured at an incident energy of 170.3 MeV. Special care was taken with the limited intensity and broad profile of the secondary beam. The measured angular distribution of the differential cross section shows that the Coulomb-nuclear interference peak (CNIP) is not suppressed in this system, in contrast to what was observed in the scattering of neutron halo nuclei by heavy targets at energies around the Coulomb barrier. Analyses of the angular distribution were performed both in terms of the optical model using a single-folding-type potential and the continuum discretized coupled-channels (CDCC) method, which explicitly takes into account the breakup-channel couplings to the elastic scattering. The overall pattern of the differential cross section is well reproduced by the CDCC calculations. The calculations show that the effect of breakup-channel couplings on the elastic scattering is small in the present case.
- Published
- 2013
5. Structural Optimization of Thermomechanical Properties for Short-Fiber-Reinforced Composites
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D. C. Stouffer and S. W. Xu
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Materials science ,Composite number ,Stiffness ,02 engineering and technology ,Fiber-reinforced composite ,Geometric shape ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Finite element method ,Stress (mechanics) ,020303 mechanical engineering & transports ,0203 mechanical engineering ,Volume fraction ,Ceramics and Composites ,medicine ,Fiber ,Composite material ,medicine.symptom ,0210 nano-technology - Abstract
Composite materials are heterogeneous materials on the microscopic level. For short-fiber reinforced composites, the fiber-matrix and fiber-fiber interactions play a significant role in the strength and global stiffness of the material. A unit cell model is developed to study the influence of fiber clustering patterns on the local stress distribution and global composite properties. Design variables are established to account for the variations in fiber clustering patterns, aspect ratio, volume fraction, and fiber packing. Design constraints are used to represent composite moduli, thermal coefficients of expansion, maximum interfacial stress and thermal residual stress. The model is analyzed by the p-version finite element method. The study is limited to elastic analysis. The p-version finite element method offers rapid convergence on localized stress fields using only coarse mesh and allows geometric shape variations without remeshing. Solution accuracy can be checked systematically using a series of solutions with increasing numerical complexity that is generated from a given mesh. A parametric study of the effect of fiber cluster patterns, fiber packing, and fiber aspect ratio is conducted. The study shows that the fiber cluster pattern and fiber packing has a significant impact on all of the composite properties studied.
- Published
- 1995
6. Effects of Zearalenone on IL-2, IL-6, and IFN-γ mRNA Levels in the Splenic Lymphocytes of Chickens
- Author
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Junliang Deng, Z. H. Ren, S. W. Xu, Wang Yingzhu, X. Peng, H. M. Cui, Z. C. Zuo, and Y. Wang
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Interleukin 2 ,medicine.medical_specialty ,Article Subject ,lcsh:Medicine ,medicine.disease_cause ,Models, Biological ,lcsh:Technology ,General Biochemistry, Genetics and Molecular Biology ,Interferon-gamma ,chemistry.chemical_compound ,Immune system ,Internal medicine ,medicine ,Animals ,Interferon gamma ,Estrogens, Non-Steroidal ,Lymphocytes ,RNA, Messenger ,Mycotoxin ,Interleukin 6 ,lcsh:Science ,Zearalenone ,General Environmental Science ,biology ,Interleukin-6 ,Toxin ,lcsh:T ,fungi ,lcsh:R ,General Medicine ,In vitro ,Endocrinology ,Gene Expression Regulation ,chemistry ,Immune System ,biology.protein ,Interleukin-2 ,lcsh:Q ,Chickens ,Research Article ,medicine.drug - Abstract
Zearalenone (ZEN) is an estrogenic mycotoxin produced by severalFusariumspecies, which can contaminate food and feed. These compounds elicit a wide spectrum of toxic effects, including the capacity to alter normal immune function. In this study, the in vitro effects of the treatment of ConA-stimulated splenic lymphocytes with ZEN (0–25 μg/mL) were examined. ZEN modulates the expression of IL-2, IL-6, and IFN-γ. The IL-2 levels were up to fourfold higher (P<0.05) compared with the levels in the control at toxin concentrations of 25 μg/mL after 48 h of treatment. The IL-6 levels were critically suppressed at this concentration; these changes were very statistically significant (P<0.05). At lower ZEN concentrations (0.1, 0.4 and 1.6 μg/mL), the IFN-γlevels changed slightly; however at 6.25 and 25 μg/mL, the IFN-γresults reached statistical significance compared with the control levels (P<0.05). These data suggest that ZEN has potent effects on the expression of chicken splenic lymphocytes cytokines at the mRNA level.
- Published
- 2012
7. Analysis of risk factors associated with outcomes in road traffic injury patients with acute lung injury
- Author
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J-X Gan, Ming Zhang, Jack S. Wu, Guan-yu Jiang, S-W Xu, and Lei Sheng
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Male ,medicine.medical_specialty ,Acute Lung Injury ,Poison control ,Lung injury ,Biochemistry ,Suicide prevention ,Occupational safety and health ,Sepsis ,Patient Admission ,Risk Factors ,Injury prevention ,Odds Ratio ,Medicine ,Humans ,Intensive care medicine ,business.industry ,Biochemistry (medical) ,Accidents, Traffic ,Human factors and ergonomics ,Cell Biology ,General Medicine ,respiratory system ,medicine.disease ,respiratory tract diseases ,Treatment Outcome ,Female ,business ,Risk assessment ,human activities - Abstract
Over 50% of road traffic injury (RTI) patients experience post-traumatic acute lung injury (ALI) and it is, therefore, extremely important to identify the risk factors related to the poor outcomes associated with ALI in RTI populations. This study evaluated 19 potential risk factors associated with the outcomes of ALI in 366 RTI patients. They were divided into two groups: a ‘favourable outcomes group’ and an ‘unfavourable outcomes group’. The results indicated that the Acute Physiology and Chronic Health Evaluation II (APACHE II) score and the presence of gastrointestinal haemorrhage may help predict the outcomes of ALI in the early post-trauma phase of treatment. The duration of trauma and sepsis were shown to impact strongly on both the short- and long-term outcomes of ALI. Age (≥ 65 years) and disseminated intravascular coagulation in the early RTI phase were also independent risk factors for a poorer short- and long-term outcome in ALI.
- Published
- 2009
8. Effects of cold stress on the messenger ribonucleic acid levels of corticotrophin-releasing hormone and thyrotropin-releasing hormone in hypothalami of broilers
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J T, Wang, J W, Wang, and S W, Xu
- Subjects
Messenger ribonucleic acid ,Male ,endocrine system ,medicine.medical_specialty ,Time Factors ,Corticotropin-Releasing Hormone ,Hypothalamus ,Thyrotropin-releasing hormone ,Biology ,Random Allocation ,Stress, Physiological ,Internal medicine ,medicine ,Animals ,RNA, Messenger ,Thyrotropin-Releasing Hormone ,Cold stress ,Regulation of gene expression ,Messenger RNA ,Base Sequence ,Broiler ,RNA ,General Medicine ,Cold Temperature ,Endocrinology ,Gene Expression Regulation ,Animal Science and Zoology ,Chickens ,hormones, hormone substitutes, and hormone antagonists ,Hormone - Abstract
In this study, seventy 1-d-old male broiler chicks were randomly allocated to 10 groups to investigate the effect of cold stress on the messenger RNA (mRNA) levels of corticotrophin-releasing hormone (CRH) and thyrotropin-releasing hormone (TRH) in hypothalami. The chicks were maintained at 30 +/- 2 degrees C temperature and given free access to standard chow and water. Until 15 d old, the 6 treatment groups were maintained at 12 +/- 1 degrees C. Hypothalami were collected for the assessment of the mRNA levels by semiquantitative reverse transcription-PCR after stress termination. Cold stress significantly decreased the mRNA levels of CRH in 6 and 12 h treatment groups and significantly increased the mRNA levels of TRH in 1, 6, and 12 h treatment groups during acute cold stress. There were no significant differences in the mRNA levels of CRH and TRH among different control groups during chronic cold stress. However, chronic cold stress resulted in a significant increase of the mRNA levels of CRH and a significant decrease of the mRNA levels of TRH compared with the corresponding control groups. The results indicate that the 2 genes show different response to cold stress at the mRNA levels, and on the other hand, the different degree of cold stress also produces different effects on the identical gene.
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- 2008
9. Locally applied simvastatin promotes fracture healing in ovariectomized rat
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Jue Wang, D. S. Yang, S. W. Xu, and R. K. Lv
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medicine.medical_specialty ,Simvastatin ,Endocrinology, Diabetes and Metabolism ,Injections, Subcutaneous ,Ovariectomy ,Osteoporosis ,Drug Evaluation, Preclinical ,Bone healing ,Rats, Sprague-Dawley ,Internal medicine ,medicine ,Animals ,Bony Callus ,Fracture Healing ,Tibia ,business.industry ,medicine.disease ,Alkaline Phosphatase ,Skeleton (computer programming) ,Hydroxymethylglutaryl-CoA reductase ,Rheumatology ,Biomechanical Phenomena ,Rats ,Radiography ,Tibial Fractures ,Apposition ,Endocrinology ,Cholesterol ,Ovariectomized rat ,Female ,Hydroxymethylglutaryl-CoA Reductase Inhibitors ,business ,medicine.drug - Abstract
Simvastatin solution was injected subcutaneously to the site of fractured tibiae of ovariectomized rats. Afterwards healing quality was evaluated by morphologic, radiographic, biomechanical, histological and histomorphometric methods at 1, 2 and 4 weeks after fracture. Results showed that locally applied simvastatin improved fracture healing. Many studies have documented an anabolic effect of hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, statins, on undisturbed bone. Reports of their effects, however, on fractured skeletal sytems have been limited. A study was, therefore, conducted to check the effects of statins on fracture healing. Simvastatin (10 mg/kg/day) was injected subcutaneously to tissue overlying the site of fractured tibiae of ovariectomized rats for a treatment period of 5 days. Vehicle reagent was used as a control. Healing quality was evaluated at 1, 2 and 4 weeks after fracture. Compared with that in the vehicle group, the callus cross-section area in simvastatin-treated rats was significantly enlarged by 21.3% (p
- Published
- 2007
10. Locally applied simvastatin promotes fracture healing in ovariectomized rat: A novel molecular mechanism
- Author
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S. W. Xu
- Subjects
medicine.medical_specialty ,business.industry ,Endocrinology, Diabetes and Metabolism ,Bone healing ,Rheumatology ,Bone resorption ,Bone remodeling ,Endocrinology ,Simvastatin ,Internal medicine ,Orthopedic surgery ,Ovariectomized rat ,medicine ,Molecular mechanism ,business ,medicine.drug - Published
- 2008
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