1. Brain reactivity to emotional stimuli in women with premenstrual dysphoric disorder and related personality characteristics
- Author
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Guangbin Wang, Tao Gong, Wang Jieqiong, Mingzhou Gao, Mingqi Qiao, Chunhong Song, Li An, Yanhong Yu, Dongmei Gao, and Fengqin Wei
- Subjects
Adult ,emotion regulation ,Aging ,Emotions ,Precuneus ,Prefrontal Cortex ,eysenck personality questionnaire ,Luteal Phase ,Personality Assessment ,behavioral disciplines and activities ,Young Adult ,Cerebellum ,Surveys and Questionnaires ,Psychoticism ,medicine ,Humans ,Middle frontal gyrus ,premenstrual dysphoric disorder ,Brain Mapping ,Extraversion and introversion ,business.industry ,anger ,Cell Biology ,medicine.disease ,Neuroticism ,Eysenck Personality Questionnaire ,Frontal Lobe ,medicine.anatomical_structure ,Superior frontal gyrus ,Case-Control Studies ,depression ,Female ,business ,Premenstrual dysphoric disorder ,Personality ,Research Paper ,Clinical psychology - Abstract
Aims: Premenstrual dysphoric disorder (PMDD) is a psychiatric condition that is associated with the menstrual cycle. Elucidation of the neural regulation mechanisms of brain reactivity to emotional stimuli among women with PMDD may inform PMDD treatment. Methods: Eighty-six women (42 PMDD, 44 healthy controls) were allocated into two groups (anger-induced group: 23 PMDD vs. 23 controls; depression-induced group: 19 PMDD vs. 21 controls). During the luteal phases of the menstrual cycle, all the women were subjected to functional magnetic resonance imaging (fMRI). fMRI resting-state scans were performed before and after the study participants had performed an emotional stimuli task. After the emotional stimuli task, emotional status of the participants were evaluated by Self-Rating Depression Scales (SDS) and Trait Anger Expression Inventory–II (STAXI-II). In addition, all the participants were requested to complete the Eysenck Personality Questionnaire (EPQ) and the Twenty-Item Toronto Alexithymia Scale (TAS-20). Results: Compared to healthy controls, all women with PMDD exhibited significantly high scores in Tas-20 (p
- Published
- 2021