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Start Over Descriptor "thyroidectomized patients" Topic medicine
2 results on '"thyroidectomized patients"'

1. Voice Handicap Index and Acoustic Parameters in Thyroidectomized Patients with and without Voice Problems

Author

Maryam Rezvani Bafroui, Bijan Khorasani, Younes Amiri-Shavaki, Mohammad Kamali, and Mohammad Sadegh Jenabi

Subjects
thyroidectomized patients, acoustic parameters, voice handicap index, voice problems, Medicine
Abstract

Background and Objective: Vocal changes are one of the most common consequences of thyroid surgery. These changes can be due to neurological or other factors. With respect to vocal changes after surgery, and the need for determination of details of the vocal problems and related consequences in the patients’ life after thyroidectomy, the aim of this study was determination of some acoustic parameters of their voice after thyroidectomy and the status of subscales of Voice Handicap Index (VHI). Methods: This study is a cross-sectional descriptive analytic and non-interventional. One voice of 32 thyroidectomized patients (23 women and 9 men) with 20-60 years of age analyzed acoustically and they completed VHI questionnaire. Results: Statistical comparison of mean scores of VHI in two groups of patients with and without vocal problem showed that mean score and standard deviation of total scores of VHI, and the scores of functional, emotional, and physical subscales in patients with voice problems are more than the other group, and the differences were significant (P=0.000). Comparison of acoustic parameters in the two groups of patients showed that F0, jitter, shimmer, and HNR were different, but the differences were not significant. According to our results, amplitude perturbations and harmonic to noise ratio was high in both groups of thyroidectomized patients. Conclusion: According to the findings of this research, we can conclude that F0, jitter, shimmer, and HNR of voice may be not enough for determination of voice problems, but other acoustic measures, self-perceptual, or self-reported evaluation tools such as VHI maybe more efficient in determination of thyroidectomized patients’ voice problems.

Published
2018

2. Recommendations for treatment of hypothyroidism with levothyroxine and levotriiodothyronine: a 2016 position statement of the Italian Society of Endocrinology and the Italian Thyroid Association

Author

Andrea Lenzi, Alfredo Pontecorvi, Furio Pacini, Stefano Mariotti, Paolo Vitti, Luca Chiovato, Francesco Trimarchi, Luigi Bartalena, Bernadette Biondi, Biondi, Bernadette, Bartalena, L, Chiovato, L, Lenzi, A, Mariotti, S, Pacini, F, Pontecorvi, A, Vitti, P, and Trimarchi, F.

Subjects
Quality of life, medicine.medical_specialty, L-Thyroxine, Hormone Replacement Therapy, Endocrinology, Diabetes and Metabolism, Levothyroxine, MEDLINE, 030209 endocrinology & metabolism, Polymorphism in type 2 deiodinase gene, Replacement therapy, 03 medical and health sciences, Thyroidectomized patients, 0302 clinical medicine, Hormone replacement therapy (female-to-male), Cognition, Endocrinology, Hypothyroidism, Internal medicine, Mood, medicine, Humans, Medical prescription, Adverse effect, Depression (differential diagnoses), Deiodinases, business.industry, Depression, Thyroid, Settore MED/13 - ENDOCRINOLOGIA, L-Triiodothyronine, Body weight, TSH-suppressive therapy, Diabetes and Metabolism, Thyroxine, Clinical symptoms, Heart rate and patient preference for combined therapy, medicine.anatomical_structure, Italy, 030220 oncology & carcinogenesis, Practice Guidelines as Topic, Triiodothyronine, business, Quality of Life, Hypothyroidism Replacement therapy TSH-suppressive therapy l-Thyroxine l-Triiodothyronine Deiodinases Clinical symptoms Quality of life Cognition Mood Depression Body weight Heart rate and patient preference for combined therapy Thyroidectomized patients Polymorphism in type 2 deiodinase gene, medicine.drug
Abstract

Levothyroxine (L-T4) is recommended as lifelong replacement therapy for hypothyroidism. Recent clinical and experimental data support the addition of levotriiodothyronine (L-T3) treatment in some selected hypothyroid patients when their symptoms persist and their quality of life remains impaired despite adequate L-T4 monotherapy. An increase in L-T3 prescriptions has been recently observed in Italy due to availability of different L-T3 formulations, making it possible to clinicians to prescribe L-T3 alone or in combination with L-T4. The aim of the present position statement was to define the correct clinical indications, schedule, duration of treatment and contraindications of combined treatment with L-T4 and L-T3 in hypothyroid patients in an attempt to guide clinicians and to avoid potential adverse effects of overtreatment.

Published
2016

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