1. An atypical localization of a Merkel cell carcinoma: A case report and review of the literature
- Author
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Jerguigue Hounayda, Iraqi Fatima Zahra, Omor Youssef, and Latib Rachida
- Subjects
Pathology ,medicine.medical_specialty ,Necrosis ,integumentary system ,medicine.diagnostic_test ,Merkel cell carcinoma ,business.industry ,medicine.medical_treatment ,Skin tumor ,Immunosuppression ,medicine.disease ,medicine.anatomical_structure ,Biopsy ,medicine ,Immunohistochemistry ,medicine.symptom ,Radical surgery ,business ,Merkel cell - Abstract
Introduction: Merkel cell carcinoma (MCC) is an aggressive skin tumor of neuroendocrine origin that derives from Merkel cells and occurs predominantly on the head or neck of elderly individuals at an average age of 69 years old. Its main risk factors are immunosuppression and ultraviolet exposure. The diagnosis is established on the histological aspect and completed by immunohistochemistry. Case Report: We report the case of a 65-year-old female patient, with no particular antecedents, who had right axillary swelling. Thoracic computed tomography (CT) showed a large right axillary mass of irregular contours, lobulated, heterogeneously enhanced after CP injection with central hypodense zone of necrosis. The confrontation of the morphological aspect and the results of the immunohistochemistry carried out made it possible to retain the diagnosis of Merkel cell carcinoma. Conclusion: Merkel cell carcinoma is a very aggressive cancer of the elderly. In case of doubt, a biopsy for histological confirmation should be performed. The therapy is usually based on a radical surgery followed by adjuvant radiotherapy.
- Published
- 2021