Search

Introduction/Aim Carbon monoxide (CO) is a gas produced by incomplete combustion of carbon compounds and is a leading cause of poising throughout the world. The objective of this paper is to analyze 5 cases of acute carbon monoxide poisoning in petroleum industry workers, occupying a shared accommodation and to present diagnostic, therapeutic and preventive measures. Case report the workers had to be treated by the emergency medical service during the night for health problems arising from carbon monoxide inhalation from a faulty installation. Venous blood samples were collected to measure the concentration of carboxyhemoglobin (COHb) and gas analyses were done upon admission and 120 minutes later. They were treated with parenteral therapy and oxygen by mask, and they made a complete recovery. Conclusion Faulty installation of a gas-powered heating system caused acute carbon monoxide poisoning in 5 people occupying the space. After 120 minutes in a closed environment, the carbon monoxide concentration was high enough to cause a significant increase of COHb in the venous blood. Prompt diagnosis and adequate therapy are crucial to ensure a favorable treatment outcome. Preventive measures, such as educating workers and introducing health and safety measures into the work environment are extremely important in preventing accidents such as these.

Sclerosing mesenteritis (SM) is a rare and poorly understood chronic benign inflammatory condition of the mesentery that sometimes can be manifested as acute abdominal emergency. In this paper sclerosing mesenteritis was discussed on the occasion of experience in the diagnosis and the treatment of patients in clinical practice, a 62-year-old man who was diagnosed SM on computed tomography (CT) which was confirmed histopathologically. SM manifests grossly as a diffuse, localized, or multinodular thickening of the mesentery. Microscopically, according to the pattern of the disease, SM can be divided into sclerosing panniculitis where necrosis and inflammation predominate and retractile mesenteritis in which fibrosis and retraction are hallmarks of the disease. Clinical presentation of patients suffering from SM is quite diverse - from asymptomatic, which is the most common, to abdominal pain, bloating, nausea, vomiting and febrile episodes. The 'fat ring sign' and peripheral pseudocapsule are virtually pathognomonic CT findings of SM. Management of SM is empirical with no guidelines yet established. SM should be listed in the differential diagnosis in every older patient with diverse abdominal complaints.

Osteoporotic bone is a bone with decreased bone density and due to that predispose for fractures. Aim. To determine frequency of risk factors, type and localization of fractures in patients with decreased bone density. Material and method. Analysis included 763 patients of both sex. Osteodensitometry was performed and data on clinical risk factors for osteoporosis and osteoporotic fractures were collected. Results. Most of patient were female (96%) and average age was 63 years. The most frequent risk factors were early menopauses, previous fractures and fractures in relatives. Most of patients with osteoporotic fractures had T score of hip on osteopenia level and type was predominantly nonvertebral. Vertebral fractures were more frequent in patients with T score -2,5 SD. Conclusion. Besides osteodensitometry finding of decreased bone density, identifying of clinical risk factors for osteoporosis is essential for early making of diagnosis of osteoporosis and prevention of osteoporotic fractures.

A 45-year-old woman was referred for CT of the abdomen due to endoscopically detected esophageal varices. The patient complained of dizziness and long-term epigastric pain. The CT scan showed five aberrant splenic nodules (Picture a), a short pancreas (Picture b, arrowhead), a preduodenal portal vein (Picture b, arrow), intestinal malrotation (Picture c) and a symmetric midline position of the liver (Picture c), all of which were consistent with a diagnosis of polysplenia syndrome. Polysplenia syndrome (PSS) is a rare congenital disease that occurs in patients with two or more spleens and various organ anomalies. Unlike that occurring in children, PSS in adults is usually asymptomatic and discovered incidentally since cardiovascular anomalies are minor or nonexistent (1). However, anomalies of the abdominal viscera sometimes lead to clinical manifestations or represent a surgery danger (2). Fortunately, conducting a careful analysis of systemic anomalies, which is required in medical evaluations, is therefore facilitated using modern imaging techniques.

Rates of fatal accidents per 100,000 workers in industry are indicators of achievement in occupational safety and health. The pattern of fatal occupational accidents varies in different regions of the world particularly in developing countries. In global estimates of fatal occupational accidents by Takala J (1999) from the International Labour Organization there are no data related to fatal occupational accidents in the Federal Republic of Yugoslavia. There are no known published studies of occupational fatalities in Yugoslavia to date. The Autonomous Province of Vojvodina is the most developed economic region in Yugoslavia. Vojvodina has an area of 21,506 km with a population of roughly 2 million. The purpose of this study was to examine the characteristics of fatal occupational injuries in the Vojvodina, the most developed region in Yugoslavia, by industry and cause of death, and the influence of the economic situation on fatal occupational injury rates in the 1990s.

Synopsis The increased incidence of congenital postural deformities among newborns with breech presentation may be associated with causes of breech presentation rather than the presentation itself.

The aim is to investigate the influence of the antidiabetic drug gliclazide on the ileal permeation of the semisynthetic bile acid, MKC, in tissues from healthy and diabetic rats. Sixteen Wistar rats (350 +/- 50 g) were randomly allocated into four groups (4 rats per group, 8 chambers per rat, i.e., n=32) two of which were made diabetic (given alloxan i.v. 30 mg/kg). Group 1 was used to measure the permeation of MKC (50 microg/ml) alone (control) while group 2 to measure MKC permeation in the presence of gliclazide (200 microg/ml). The diabetic groups 3 (gliclazide) and 4 (MKC+gliclazide) were treated in the same way. Rats were sacrificed and tissues were mounted into the Ussing chamber for the measurement of MKC mucosal to serosal (absorptive) and serosal to mucosal (secretory) fluxes. In healthy tissues, gliclazide reduced MKC absorptive flux (p0.01) and increased its secretory flux (p0.01). In diabetic tissues, gliclazide had no effect on either the absorptive or the secretory fluxes of MKC. The lack of effect of gliclazide on MKC permeation in diabetic tissues suggests the absence or suppressed drug transporters. Furthermore, gliclazide inhibition of MKC absorptive flux and induction of MKC secretory flux in healthy tissues may result from the selective inhibition of an efflux drug transporter.