1. Antinukleäre Antikörper
- Author
-
Bettina Santler and Jan Ehrchen
- Subjects
musculoskeletal diseases ,medicine.medical_specialty ,Anti-nuclear antibody ,business.industry ,Autoantibody ,Dermatology ,Dermatomyositis ,medicine.disease ,Laboratory results ,stomatognathic diseases ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,immune system diseases ,030220 oncology & carcinogenesis ,Medicine ,In patient ,skin and connective tissue diseases ,business - Abstract
Antinuclear antibodies (ANA) are a common diagnostic finding in patients with systemic autoimmune diseases. In patients with typical clinical symptoms, the determination of ANA is of both diagnostic and prognostic importance. However, if ANA were determined due to unspecific symptoms, the interpretation of ANA findings can be problematic. In these cases, misjudgements with severe consequences for the patients are possible. Many systemic autoimmune diseases have prominent early skin involvement and the dermatologist can be the first physician that such a patient sees. Therefore, knowledge of ANA diagnostics is important for dermatologists. Basic principles of autoantibody diagnostics, guidance for the interpretation of laboratory results and new developments are discussed in this overview.
- Published
- 2020