1. Altered Mental Status: An Important but Overlooked Presenting Symptom of COVID-19 in Older Adults
- Author
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Sabrina Rosengarten, Pia Daniel, Max Mecklenburg, Igal Brietman, Alvin Oommen, Rohan Maini, Priyanka Parmar, Julie Minjae Kim, Clara Wilson, and Joel Thomas
- Subjects
medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,medicine.medical_treatment ,Single Center ,03 medical and health sciences ,AKI ,0302 clinical medicine ,Altered Mental Status ,Internal medicine ,Humans ,Medicine ,Intubation ,In patient ,AMS ,Mortality ,Pandemics ,Aged ,Retrospective Studies ,Geriatrics ,Pandemic ,030214 geriatrics ,SARS-CoV-2 ,business.industry ,Brief Report ,Acute kidney injury ,COVID-19 ,Acute Kidney Injury ,medicine.disease ,Psychiatry and Mental health ,Observational study ,Geriatrics and Gerontology ,business - Abstract
Objectives To determine whether altered mental status (AMS) as a presenting symptom in older adults with COVID-19 is independently associated with adverse outcomes. Methods A retrospective single center observational study of admitted patients (n = 421) age greater than 60 and a positive COVID-19 test. Outcomes included mortality, intubation, acute respiratory distress syndrome, acute kidney injury, and acute cardiac injury. Multivariate regression analysis was used to determine if presenting with AMS was associated with adverse outcomes. Results There was an increased risk of mortality (RR 1.29, 95% CI 1.05–1.57), intubation (RR 1.52, 95% CI 1.09–2.12) and AKI (RR 1.42, 95% CI 1.13–1.78) in patients that presented with AMS. Conclusions During a global pandemic, prognostic indicators are vital to help guide the clinical course of patients, reduce healthcare cost, and preserve life. Our study suggests that AMS can play a major role in diagnostic algorithms in older adults with COVID-19.
- Published
- 2021