1. Direct comparison of rest and adenosine stress myocardial perfusion CT with rest and stress SPECT
- Author
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Ammar Sarwar, Ricardo C. Cury, Brian B. Ghoshhajra, Ron Blankstein, Udo Hoffmann, Hiram G. Bezerra, Leonid D. Shturman, Thomas J. Brady, Jose A. Rocha-Filho, David R. Okada, Wilfred Mamuya, Henry Gewirtz, and Ian S. Rogers
- Subjects
Male ,Adenosine ,Rest ,Vasodilator Agents ,Adenosine stress ,Ischemia ,Coronary Artery Disease ,Sensitivity and Specificity ,Article ,Stress imaging ,Myocardial perfusion imaging ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Rest (music) ,Tomography, Emission-Computed, Single-Photon ,medicine.diagnostic_test ,business.industry ,Myocardial Perfusion Imaging ,Reproducibility of Results ,Middle Aged ,Image Enhancement ,medicine.disease ,Vasodilator agents ,Dual source computed tomography ,Exercise Test ,Female ,Tomography, X-Ray Computed ,Cardiology and Cardiovascular Medicine ,business ,Nuclear medicine ,Perfusion - Abstract
We have recently described a technique for assessing myocardial perfusion using adenosine-mediated stress imaging (CTP) with dual source computed tomography. SPECT myocardial perfusion imaging (SPECT-MPI) is a widely utilized and extensively validated method for assessing myocardial perfusion. The aim of this study was to determine the level of agreement between CTP and SPECT-MPI at rest and under stress on a per-segment, per-vessel, and per-patient basis. Forty-seven consecutive patients underwent CTP and SPECT-MPI. Perfusion images were interpreted using the 17 segment AHA model and were scored on a 0 (normal) to 3 (abnormal) scale. Summed rest and stress scores were calculated for each vascular territory and patient by adding corresponding segmental scores. On a per-segment basis (n = 799), CTP and SPECT-MPI demonstrated excellent correlation: Goodman-Kruskall γ = .59 (P
- Published
- 2009
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