1. Pleomorphic liposarcoma with liver metastasis diagnosed by combined fine-needle aspiration cytology and core-needle biopsy
- Author
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Valeria Ciliberti, Pasquale Cretella, Pio Zeppa, Alessandro Caputo, Ciliberti, V., Cretella, P., Zeppa, P., and Caputo, A.
- Subjects
pleomorphic liposarcoma ,Pathology ,medicine.medical_specialty ,Histology ,Biopsy, Fine-Needle ,Context (language use) ,Soft Tissue Neoplasms ,core-needle biopsy ,Liposarcoma ,Pleomorphic Liposarcoma ,Pathology and Forensic Medicine ,Metastasis ,fine-needle cytology ,liver metastasis ,Biopsy ,Medicine ,Humans ,liver metastasi ,medicine.diagnostic_test ,business.industry ,Liver Neoplasms ,Soft tissue ,General Medicine ,medicine.disease ,Primary tumor ,body regions ,Concomitant ,Biopsy, Large-Core Needle ,business - Abstract
Pleomorphic liposarcoma (PLPS) is the rarest liposarcoma subtype, with high-local recurrence and metastasis rates. Fine-needle aspiration cytology (FNAC) is successfully used in the diagnosis of primary or metastatic soft tissue tumors, but liver metastases of PLPS diagnosed by FNAC have never been reported. The cytological diagnosis depends on the identification of lipoblasts with sharply defined cytoplasmic vacuoles indenting and distorting the nucleus in the context of a pleomorphic tumor and in a proper clinical and imaging context. Despite its aggressive behavior, hematogenous liver metastases are rare, with just one case reported in literature. A case of PLPS liver metastasis and concomitant primary tumor diagnosed by FNAC and core needle biopsy is herein described.
- Published
- 2021