1. Predictive Factors of Surgical Complications in the First Year Following Kidney Transplantation
- Author
-
Sébastien Déglise, Jean-Marc Corpataux, Jean-Pierre Venetz, Céline Deslarzes-Dubuis, Séverine Petitprez, Alban Longchamp, and Pauline Salamin
- Subjects
medicine.medical_specialty ,Kidney ,Multivariate analysis ,Surgical complication ,business.industry ,Graft Survival ,General Medicine ,University hospital ,medicine.disease ,Kidney Transplantation ,Tissue Donors ,Surgery ,Treatment Outcome ,surgical procedures, operative ,medicine.anatomical_structure ,medicine ,Clinical endpoint ,Humans ,Graft survival ,Cardiology and Cardiovascular Medicine ,business ,Kidney transplantation ,Dyslipidemia ,Retrospective Studies - Abstract
Background In the recent years, an increased use of marginal donors and grafts and a growing prevalence of peripheral arterial disease in the recipients have been observed. Meanwhile, the open surgical technique for kidney transplantation has not changed. The aim of this study is to analyze all surgical complications occurring in the first year after kidney transplant and to determine potential predictive risk factors. Method Data of the 399 patients who underwent kidney transplant in our University Hospital between January 2006 and December 2015 were retrospectively reviewed. The primary endpoint was the overall rate of vascular, parietal and urological complications at 1 year following kidney transplantation. The secondary outcomes were graft and patient’ survival rates, and the identification of predictive factors of the surgical complications. Results Twenty-four percent of patients developed 134 complications. Vascular complication represented 39% of all complications and resulted in 9 graft losses. Parietal and urological complications represented 46% and 15% of all complications, respectively, No parietal or urological complications were associated with graft loss. Five patients died during the first year, none of these cases was associated with graft loss. The graft survival rate reached 96% at 1 year, including patients still alive. The occurrence of surgical complication was associated with reduced graft survival at 1 year. Using a multivariate analysis, 4 predictive factors were identified: age, deceased donor, operative time and dyslipidemia. Conclusion Surgical complications after kidney transplantation remained frequent and age, deceased kidney donors, and operative time were identified as risk factors. As vascular complications were a major cause of early graft loss, efforts should aim to reduce their occurrence to increase graft survival.
- Published
- 2022