1. Comparative study of open and laparoscopic Kasai portoenterostomy in children undergoing living donor liver transplantation for biliary atresia
- Author
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Yusuke Yanagi, Akinari Fukuda, Mureo Kasahara, Hiroo Uchida, Atsuyuki Yamataka, Masahiro Takeda, Seiichi Shimizu, Seisuke Sakamoto, and Hajime Uchida
- Subjects
Surgical results ,medicine.medical_specialty ,medicine.medical_treatment ,Portal vein ,Portoenterostomy, Hepatic ,Liver transplantation ,Biliary Atresia ,Biliary atresia ,Pediatric surgery ,Living Donors ,medicine ,Humans ,Child ,Retrospective Studies ,business.industry ,Infant ,General Medicine ,medicine.disease ,Liver Transplantation ,Surgery ,Treatment Outcome ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Propensity score matching ,Laparoscopy ,Hepatectomy ,Living donor liver transplantation ,business - Abstract
The effectiveness of laparoscopic Kasai portoenterostomy (Laparoscopic-KPE) for biliary atresia (BA) has been reported but remains controversial. We reviewed our own cases and cases described in previous studies of liver transplantation (LT) for BA after Laparoscopic-KPE to investigate the efficacy of Laparoscopic-KPE. Subjects were children of ≤ 2 years old with LT for BA after KPE who underwent Laparoscopic-KPE (n = 10) or Open-KPE (n = 115) between 2009 and 2020. Propensity score matching was performed to reduce the effect of treatment selection bias. The clinical data regarding the preoperative characteristics and surgical results were compared. The rates of hypoplastic portal vein and retrograde portal vein flow were lower in the Laparoscopic-KPE group than in the Open-KPE group (0 vs. 40.0%, p = 0.02 and 0 vs. 35.0%, p = 0.04). There was no marked difference in the operation time or duration of hepatectomy. For portal vein reconstruction, a vein graft was not required in the Laparoscopic-KPE group (0 vs. 35.0%, p = 0.03). No patients in the Laparoscopic-KPE group developed portal vein complications or required re-laparotomy for bowel perforation or re-bleeding, in contrast to the Open-KPE group (0 vs. 15.0% and 0 vs. 10.0%, respectively). Laparoscopic-KPE may reduce postoperative complications that necessitate re-laparotomy in LT.
- Published
- 2021
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