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ObjectiveThis case is a presentation of three siblings diagnosed as affective disorder with polycythaemia vera during the episodes. Polycythaemia dissappearing with the remission of affective disorder is focus of attention of these cases.Method and resultsFirst sister is 28 years old, single, treated for manic and subclinic depressive episodes for almost ten years. Polycythaemia vera has been developed with beginning of every manic episode and disappeared with the remission of episode. The patient made venopunction of 500cc weekly during the manic episode. Second brother is 26 years old, single, polycythaemia and psychotic depression were developed rapidly after a stressful life event. Venopunction was made for four times during one month medication. Polycythaemia and depression remitted at the same time. Third brother is 24 years old, single, polycythaemia and nonpsychotic depression were developed after his brother's depression. Venopunction was made for three times during three weeks of treatment. Again polycythaemia and depression remitted at the same time.ConclusionThe siblings had no internal disease. Only first sister was on lithium treatment, 600mg/day for chronic affective disorder but her first polycythaemia attack was prior to lithium treatment. We found only one report upon the relationship between affective disorder and polycythaemia vera in which mania, delirium and polycythaemia rubra vera were documented. #Freeman MP, Wiegand C, Gelenberg AJLithium. İn Textbook of Psychopharmacology. Third Edition. Schatzberg AF, Nemenoff CB (editors) American Psychiatric Publishing, Washington DC. 2004, 547-565.

ObjectiveKartagener's Syndrome is a rare congenital malformation and characterized by the triad of bronchiectasis, sinusitis, and situs inversus. We presented a case diagnosed as Kartagener's syndrome and psychotic disorder not elsewhere specified.Method and resultsThe case was a male patient, 32 years old, high school educated, married, with two children. He had a history with increasing psychotic symptoms and two times of suicide attempts for the last two months needed hospitalisation. In the psychiatric examination affect was blunted, there were anxiety, fear due to auditive hallusinations and referance delusions, anhedonia, suicidal thoughts and attempts, secondary depression. Psychiatric disorder predominently with auditive hallusinations and social withdrawal had a duration of three years. He was diagnosed as Kartagener's Syndrome when he was nine years old. The patient was treated with haloperidol 20 mg/day, biperiden 5 mg/day, klorpromazin 100 mg/day during hospitalisation. The psychotic symptoms were reduced within third day. On radiography his heart was seen at the right side of his body, there was bronchial dilatation in the medial and inferior lobes of left lung, thickness of walls of bronches and increased peribronchial density.ConclusionWe assume that the biochemical disorder that is the cause of the development of Kartegener Syndrome is related with the genetic location which facilitates the development of psychosis or risk of psychosis.

IntroductionCarcinoebmryonic antigen (CEA) is mostly used to detectearly recurrences after surgery in patients with colorectalcancer [1]. In this report, we present a case in whichparoxetine use caused increase in CEA. In literature, asimilar case has not been previously presented.CaseA 61-year-old male patient, married, with a child, sufferedtwo depressive episodes, with the first one occurring 15years ago and the second one 7.5 years ago. After thesecond episode, he received paroxetine treatment for ayear, but 6 months after the cessation of treatment, a thirddepressive episode occurred, and paroxetine was startedagain at 20 mg/day. After a response was obtained, hecontinued to use 10 mg/day. Six years after the lastepisode, in routine controls, CEA levels began to increase.CEA level was 20 in April 2008, 27 in June 2008 and 34in September 2008. A whole-body cancer screening wasperformed. However, clinical examination and laboratorytests [computed tomography (CT) and ultrasound (US)]did not reveal cancer. Therefore, in this patient, theincrease in CEA was attributed to paroxetine, and thetreatment was discontinued. A month later, CEA levelbecame 17.DiscussionCEA increase during paroxetine use may be related to theincrease in serotonin, serotonin