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nkylosing spondylitis (AS), also known as Marie-Strum- pell disease, is a member of the family of spondyloar- thritides, which include psoriatic arthritis, reactive arthritis, and arthritis related to inflammatory bowel disease. AS was first reported in 1897 (21) and has a prevalence of 0.1%e 1.4%. It is twice as common in male patients compared with female patients (7); typically affects patients between 20 and 40 years old; and is generally symptomatic causing joint pain, including back pain and stiffness (2).

yringomyelia is a rare neurological disorder estimated to affect 9 per 100,000 people in the population (4) that reS sults from pathologic cyst formation within the spinal cord. The classic presentation includes a dissociated and/or suspended progressive sensory loss in a cape-like distribution with spasticity, lower-limb hyperreflexia, and neuropathic pain. Syringomyelia occurs, however, in association with a spectrum of clinical conditions, variable spinal cord anatomical localization, and diverse histopathological patterns. To reflect this variation, it can be classified as follows: 1) communicating central canal syrinx; 2) noncommunicating central canal syrinx; 3) atrophic cavitations; and 4) neoplastic cavitations (11).

Lymphocytic hypophysitis (LH) is a rare inflammatory disorder of the pituitary gland that typically affects women in the peripartum period. We describe two male patients (ages 43 years and 36 years), who presented with headaches, visual disturbance and hypopituitarism. MRI revealed a heterogeneous pituitary lesion that extended into the suprasellar region and with a thickened pituitary stalk. In both patients a histopathological diagnosis of LH was made after endoscopic transsphenoidal surgery. LH in males, although rare, should be considered as a differential diagnosis in those with hypopituitarism and a heterogeneous pituitary fossa mass, extending into pituitary stalk.