1. Association between periodontitis and vitamin D status: A case-control study
- Author
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Abdullah Ali H Alzahrani, Ghalia Shamlan, Raed A. Alharbi, Abdulmajeed Abdulghani A. Sindi, Mohammed Abdullah Alzahrani, Mohammed A. Sindi, Mohammad A Albanghali, and Faisal A. Alzahrani
- Subjects
0106 biological sciences ,0301 basic medicine ,medicine.medical_specialty ,Disease prevention ,Periodontal examination ,QH301-705.5 ,Epidemiology ,vitamin D ,01 natural sciences ,vitamin D deficiency ,03 medical and health sciences ,Genetic ,ESCPG, the Endocrine Society Clinical Practice Guidelines ,AL, Attachment Loss ,Internal medicine ,Vitamin D and neurology ,Medicine ,OR, Odd Ratio ,Biology (General) ,Periodontitis ,VDR, Vitamin D Receptor ,25(OH)D, Serum level of 25-hydroxyvitamin D ,Public health ,business.industry ,Case-control study ,medicine.disease ,030104 developmental biology ,Original Article ,PD, Probing Depth ,BMI, Body Mass Index ,General Agricultural and Biological Sciences ,business ,BMI - Body mass index ,010606 plant biology & botany - Abstract
Vitamin D deficiency and periodontitis are commonly prevalent among Saudi adults. However, the association between periodontitis and vitamin D status has not been well documented. This study aims to examine the association between periodontitis and vitamin D status among adults in the Albaha region of Saudi Arabia. A case-control study of 123 Saudi adults was conducted; 60 had severe or moderate periodontitis, and 63 were periodontally healthy. Data was collected by an online self-reported sociodemographic questionnaire. All participants then underwent a full periodontal examination. Blood samples were also provided to assess participants’ vitamin D statuses through serum levels of 25-hydroxyvitamin D (25(OH)D). A total of 60 cases and 63 controls matched for BMI (30.2 ± 4.86 kg/m2), age (40.01 ± 7.73 years), and sex (46.3% and 53.7% male and female, respectively) participated in the study. Mean levels of 25(OH)D were significantly lower in periodontitis participants than in controls (25.03 ± 8.55 ng/ml, 29.19 ± 12.82 ng/ml, p = 0.037, respectively). Lower odds of periodontitis were detected per unit of 25(OH)D level (OR 0.964, 95% CI; 0.931–0.999, p = 0.043). In conclusion, periodontitis is significantly associated with deficient and insufficient levels of vitamin D among Saudi adults in the Albaha region. Future longitudinal research with a larger sample size may be suggested to confirm these results.
- Published
- 2021