1. Procedural efficacy and safety of standardized, ablation index guided fixed 50 W high‐power short‐duration pulmonary vein isolation and substrate modification using the CLOSE protocol
- Author
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Alexander Francke, Nadja S Taha, Frank Scharfe, Carsten Wunderlich, Steffen Schoen, and Marian Christoph
- Subjects
medicine.medical_specialty ,Esophageal temperature ,medicine.diagnostic_test ,business.industry ,Esophagogastroduodenoscopy ,medicine.medical_treatment ,Anterior wall ,Ablation ,Pulmonary vein ,Surgery ,Treatment Outcome ,Pulmonary Veins ,Recurrence ,Physiology (medical) ,Atrial Fibrillation ,Catheter Ablation ,medicine ,Humans ,Cardiology and Cardiovascular Medicine ,Complication ,business ,Short duration ,Substrate modification - Abstract
INTRODUCTION Ablation index (AI)-guided ablation according to the CLOSE protocol is very effective in terms of chronic pulmonary vein isolation (PVI). However, the optimal radiofrequency (RF) power remains controversial. Here, we thought to investigate the efficiency and safety of an AI-guided fixed circumferential 50 W high-power short-duration (HPSD) PVI using the CLOSE protocol. METHODS AND RESULTS In a single-center trial, 40 patients underwent randomized PVI using AI-guided ablation without esophageal temperature monitoring. In 20 patients a CLOSE protocol guided fixed 50 W HPSD was followed irrespective of the anatomical localization. Twenty subjects were treated according to the CLOSE protocol with standard power settings (20 W posterior and 40 W roof and anterior wall). In addition, 80 consecutive patients were treated according to the HPSD protocol to gather additional safety data. All patients underwent postprocedural esophagogastroduodenoscopy to reveal esophageal lesions (EDELs). The mean total procedural time was 80.3 ± 22.5 in HPSD compared to control 109.1 ± 27.4 min (p
- Published
- 2021