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OBJECTIVE Cultural adaptation of the tinnitus handicap inventory questionnaire to the Moroccan dialect version. METHOD We conducted a prospective study over a 3 years period (January 2017-January 2020) in the Otolaryngology Department of Casablanca University hospital. Translation was produced by a forward-backward procedure with analysis of the psychometric properties of the Moroccan version of the tinnitus handicap inventory. RESULTS The final Moroccan version of Tinnitus Handicap Inventory (THI) was given to 83 otosclerosis patients suffering from tinnitus. They filled the questionnaire twice before surgery and 1 year after surgery.The item-total correlations are all statistically significant (p

Resume Introduction Le traitement de la leucemie myeloide chronique (LMC) a ete revolutionne par l’avenement des inhibiteurs de tyrosine kinase. Les resultats de l’essai IRIS ont demontre l’efficacite et la tolerance a long terme de l’Imatinib. L’objectif de notre travail etait de rapporter les resultats a 15 ans du traitement de la LMC par l’Imatinib au Maroc. Patients et methodes Etude retrospective realisee au service d’hematologie du CHU d’Ibn-Rochd a Casablanca, du janvier 2003 a septembre 2018, incluant tous les patients LMC en phase chronique traites par Imatinib pendant une duree minimale de 6 mois. Resultats Au total, 318 patients ont ete colliges, la mediane d’âge etait de 41,5 ans avec un sexe-ratio H/F de 0,7. Le score de Sokal etait eleve dans 56 % des cas. La reponse hematologique complete a 3 mois etait de 92 %, la reponse cytogenetique complete a 12 mois et la reponse cytogenetique complete cumulative etaient obtenues dans 43 % (29/67) et 55 % (153/279) des cas respectivement, la reponse moleculaire etait evaluee chez 125 patients dont 85 % etaient en reponse moleculaire majeure. Sur un recul median sous traitement de 44 mois, la survie globale et la survie sans evenement a 10 ans etaient de 86 % et 59 %, respectivement. Discussion Notre profil est caracterise par un âge jeune des patients, la predominance feminine et un score de Sokal eleve. Le taux de reponse cytogenetique complete reste inferieur par rapport a ce qui est decrit ; cependant, les taux de survie ainsi que la tolerance sont semblables a ceux de la litterature.

We report the case of a patient with recurrent pterygo-palatal angiofibroma and its treatment. A 21-year-old male patient had a long history of recurrent epistaxis with progressive nasal obstruction. He was diagnosed with an angiofibroma centered in the right pterygo-palatine fossa. Initially, he underwent surgical excision with removal of the entire tumor. The evolution was clinically good with no signs of recurrence on the cervico-facial scan of control (CT). Nine months after, he presented a reappearance of epistaxis. A cervico-facial MRI was performed and showed a recurrence of the tumor process, which this time was considered inextirpable, hence the decision to opt for radiotherapy with intensity modulated radiation therapy (IMRT). He has improved clinically with a clear reduction in tumor mass on CT scan. This technique represents an interesting alternative to overcome anatomical complexity of the region, cover the tumor and preserve the organs at risk.