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Skin cancer is one of the deadliest cancers, and it has been widely developed worldwide since the last decade. Malignant melanoma is currently the most deadly skin cancer. If malignant melanoma is diagnosed at an early stage, the probability of patients being cured will be greatly improved. At present, most existing skin lesion image classification methods only use deep learning. However, the multi‐modal features of skin lesions in the medical domain are not well utilized and integrated. To reduce the classification error of the skin lesion images caused by the complexity and subjectivity of visual interpretation, a malignant melanoma dermoscopy image classification method based on multi‐modal medical features is proposed in this paper which is inspired by the fuzzy decision‐making process of doctors. It can reduce the subjective difference in the image classification process and assist dermatologists to analyze the skin lesion area. Firstly, the feature detection method based on the extension theory can effectively quantify the difference between different colour features. Then, an interpretable segmentation edge of the skin lesion is established by using the neutrosophic theory which can convert the image into the neutrosophic space. The edge of the skin lesion is captured by applying the Hierarchical Gaussian Mixture Model (HGMM) method. Next, the edge sequence is established by segmenting the edge, and the contour regularity, symmetry, and uniformity of the edge of the skin lesion are analyzed. Finally, the extracted multi‐feature sets are used for dermoscopy image classification. Experiments are carried out on real datasets, and the classification accuracy of four kernel functions is verified. The experimental results show that the authors' method can effectively improve the classification accuracy of benign dermoscopy images and malignant dermoscopy images. [ABSTRACT FROM AUTHOR]

Skin lesion segmentation is the first and indispensable step of malignant melanoma recognition and diagnosis. At present, most of the existing skin lesions segmentation techniques often used traditional methods like optimum thresholding, etc., and deep learning methods like U-net, etc. However, the edges of skin lesions in malignant melanoma images are gradually changed in color, and this change is nonlinear. The existing methods can not effectively distinguish banded edges between lesion areas and healthy skin areas well. Aiming at the uncertainty and fuzziness of banded edges, the neutrosophic set theory is used in this paper which is better than fuzzy theory to deal with banded edge segmentation. Therefore, we proposed a neutrosophy domain-based segmentation method that contains six steps. Firstly, an image is converted into three channels and the pixel matrix of each channel is obtained. Secondly, the pixel matrixes are converted into Neutrosophic Set domain by using the neutrosophic set conversion method to express the uncertainty and fuzziness of banded edges of malignant melanoma images. Thirdly, a new Neutrosophic Entropy model is proposed to combine the three memberships according to some rules by using the transformations in the neutrosophic space to comprehensively express three memberships and highlight the banded edges of the images. Fourthly, the feature augment method is established by the difference of three components. Fifthly, the dilation is used on the neutrosophic entropy matrixes to fill in the noise region. Finally, the image that is represented by transformed matrix is segmented by the Hierarchical Gaussian Mixture Model clustering method to obtain the banded edge of the image. Qualitative and quantitative experiments are performed on malignant melanoma image dataset to evaluate the performance of the NeDSeM method. Compared with some state-of-the-art methods, our method has achieved good results in terms of performance and accuracy. [ABSTRACT FROM AUTHOR]

A skin lesion is a part of the skin that has abnormal growth on body parts. Early detection of the lesion is necessary, especially malignant melanoma, which is the deadliest form of skin cancer. It can be more readily treated successfully if detected and classified accurately in its early stages. At present, most of the existing skin lesion image classification methods only use deep learning. However, medical domain features are not well integrated into deep learning methods. In this paper, for skin diseases in Asians, a two-phase classification method for skin lesion images is proposed to solve the above problems. First, a classification framework integrated with medical domain knowledge, deep learning, and a refined strategy is proposed. Then, a skin-dependent feature is introduced to efficiently distinguish malignant melanoma. An extension theory-based method is presented to detect the existence of this feature. Finally, a classification method based on deep learning (YoDyCK: YOLOv3 optimized by Dynamic Convolution Kernel) is proposed to classify them into three classes: pigmented nevi, nail matrix nevi and malignant melanomas. We conducted a variety of experiments to evaluate the performance of the proposed method in skin lesion images. Compared with three state-of-the-art methods, our method significantly improves the classification accuracy of skin diseases. [ABSTRACT FROM AUTHOR]