11 results on '"Timonen M"'
Search Results
2. Adult Patients with Atopic Eczema have a High Burden of Psychiatric Disease: A Finnish Nationwide Registry Study.
- Author
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Kauppi S, Jokelainen J, Timonen M, Tasanen K, and Huilaja L
- Subjects
- Adolescent, Adult, Aged, Case-Control Studies, Comorbidity, Female, Finland epidemiology, Humans, Male, Middle Aged, Prevalence, Registries, Sex Factors, Young Adult, Dermatitis, Atopic epidemiology, Dermatitis, Atopic psychology, Mental Disorders epidemiology
- Abstract
Atopic dermatitis is associated with several comorbidities. Epidemiological studies on psychiatric comorbidities in adult atopic dermatitis patients are sparse. We analyzed psychiatric comorbidities in a Finnish nationwide adult atopic dermatitis cohort. The study included 57,690 adult patients with atopic dermatitis as cases and 40,363 individuals diagnosed with melanocytic naevi as controls. Data was obtained from the statutory Finnish Care Register for Health Care. The prevalence of preselected comorbidities between the atopic dermatitis and control groups was compared. Every psychiatric disorder studied was more common in patients with atopic dermatitis than in controls. At least one psychiatric diagnosis was found in 17.2% of the atopic dermatitis patients and 13.1% of controls. Psychiatric morbidity is significant in patients with atopic dermatitis and therefore assessing patients' mental health status should be considered as part of standard care.
- Published
- 2019
- Full Text
- View/download PDF
3. Somatic and psychiatric comorbidities of hidradenitis suppurativa in children and adolescents.
- Author
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Tiri H, Jokelainen J, Timonen M, Tasanen K, and Huilaja L
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- Adolescent, Age Factors, Case-Control Studies, Child, Child, Preschool, Comorbidity, Female, Finland epidemiology, Humans, Male, Prevalence, Registries, Retrospective Studies, Young Adult, Hidradenitis Suppurativa epidemiology, Hidradenitis Suppurativa psychology, Mental Disorders epidemiology, Nevus, Pigmented epidemiology, Skin Neoplasms epidemiology
- Abstract
Background: Hidradenitis suppurativa (HS) is associated with various somatic and psychiatric comorbidities. Data regarding comorbidities in young patients with HS are sparse., Objective: We analyzed both somatic and psychiatric comorbidities in young patients in a nationwide HS cohort., Methods: In this retrospective case-control study, data from cases of HS in young (age 5 to <18 years) patients and age-matched controls with benign melanocytic nevi were collected from the Finnish Care Register for Health Care. The prevalence of preselected comorbidities was compared between the HS and control groups., Results: A total of 153 HS cases were found in the specified age group. Of these, 34.0% had at least 1 somatic comorbidity compared with 4.9% of the controls. At least 1 of the preselected psychiatric diagnoses was present before the age of 18 years in 15.7% of case patients with HS compared with in 5.6% of the controls. By the age of 23 years, 23.5% of the patients with HS and 8.7% of the controls had at least 1 identified psychiatric comorbidity., Limitations: Despite this being one of the largest HS cohorts ever studied, the number of young patients with HS was relatively low. Because this was a registry-based study, it was not possible to verify the accuracy of the International Classification of Diseases codes., Conclusion: Physicians should monitor young patients with HS for both somatic and psychiatric comorbidities., (Copyright © 2018 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.)
- Published
- 2018
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4. Psychiatric and neurological disorders are associated with bullous pemphigoid - a nationwide Finnish Care Register study.
- Author
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Försti AK, Jokelainen J, Ansakorpi H, Seppänen A, Majamaa K, Timonen M, and Tasanen K
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- Aged, Aged, 80 and over, Female, Finland epidemiology, Humans, Male, Middle Aged, Retrospective Studies, Mental Disorders epidemiology, Nervous System Diseases epidemiology, Pemphigoid, Bullous epidemiology, Registries
- Abstract
Bullous pemphigoid (BP) is an autoimmune blistering skin disease with increasing incidence. BP is associated with neurological disorders, but it has not been established, what subtypes of dementia and stroke are associated with BP, and what is the temporal relation between these diseases. Also, the association between BP and psychiatric disorders is controversial. We conducted a retrospective nationwide study, using the Finnish Care Register for Health Care diagnoses between 1987 and 2013. The study population of 4524 BP patients were compared with 66138 patients with basocellular carcinoma (BCC), neurological and psychiatric comorbid disorders were evaluated for both groups, and associations were estimated by Cox regression and logistic regression analyses. The strongest risk of developing BP was found after diagnosis of multiple sclerosis (MS) (OR=5.9, 95% CI 3.9-8.5). Among psychiatric diseases, the corresponding risk was strongest in schizophrenia (OR=2.7, 95% CI 2.0-3.5), and as a novel finding, also personality disorders (OR=2.2, 95% CI 1.3-3.3) preceded BP. In conclusion, many psychiatric disorders, especially schizophrenia, carry heightened risk for BP. Furthermore, several neurological diseases which cause central nervous system inflammation or degeneration were related to BP, and the association was strongest between MS and BP.
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- 2016
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5. Temporal association of onset of daily smoking with adolescent substance use and psychiatric morbidity.
- Author
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Ilomäki R, Riala K, Hakko H, Lappalainen J, Ollinen T, Räsänen P, and Timonen M
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- Adolescent, Age Factors, Age of Onset, Alcoholism epidemiology, Anxiety Disorders epidemiology, Attention Deficit and Disruptive Behavior Disorders epidemiology, Comorbidity, Conduct Disorder epidemiology, Depressive Disorder epidemiology, Female, Finland, Health Surveys, Hospitalization statistics & numerical data, Humans, Male, Psychotic Disorders epidemiology, Sex Factors, Mental Disorders epidemiology, Smoking epidemiology, Substance-Related Disorders epidemiology
- Abstract
Objective: The association between cigarette smoking and psychiatric disorders is well established for adult populations. However, only limited number of studies has investigated whether the young onset age of daily smoking (DS) among adolescents is associated with psychiatric morbidity and vice versa., Methods: Data from 508 adolescents admitted to psychiatric hospitalization were collected. Cox proportional hazard model were used to compare the initiation of DS between adolescents with and without substance use (SUD), and other psychiatric disorders., Results: Rates of DS were high in each diagnostic category. Boys started smoking at younger age (mean 12.4 years) than girls (13.0 years). Both boys and girls diagnosed with conduct or oppositional defiant disorders (COD) and also girls with SUD started daily smoking earlier as compared to those of same gender without these disorders.COD were found to be primary to the initiation of DS among boys. SUD, psychotic, and depressive disorders (DEP) were found to be secondary to DS among both genders., Conclusions: DS in adolescence is related with later SUD. COD are associated with subsequent initiation of DS among boys. The temporal gap between smoking initiation and COD is shorter among girls. Gender difference plays a role in association of DS and DEP. Initiation of DS at very early age should alert health care professionals of development of later psychopathology, especially SUD.
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- 2008
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6. Nicotine use and dependence and their association to psychiatric disorders in a large sample of adolescent psychiatric inpatients.
- Author
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Hakko H, Lintunen J, Lappalainen J, Mäkikyrö T, Räsänen P, and Timonen M
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- Adolescent, Child, Diagnostic and Statistical Manual of Mental Disorders, Female, Hospitalization, Humans, Male, Psychometrics, Regression Analysis, Sensitivity and Specificity, Tobacco Use Disorder psychology, Mental Disorders diagnosis, Schizophrenic Psychology, Surveys and Questionnaires standards
- Abstract
The purpose of this research was to evaluate the level of nicotine dependence (ND) and to examine its association to psychiatric disorders in a representative clinical sample of adolescent psychiatric inpatients. The modified Fagerstrom Tolerance Questionnaire (mFTQ) was used to assess the level of ND. Psychiatric DSM-IV diagnoses were obtained by using the Schedule for affective disorder and schizophrenia for school-age children (K-SADS-PL). Of the total of 342 inpatients in the study sample, 259 (75.7%) reported to be current smokers. A sum score 6 or higher in the mFTQ, indicating a high level of ND, was found in 37.9% of all smokers. An increased likelihood for high level of ND was associated with substance related disorders (OR 5.1, 95% CI 2.8-9.3), conduct disorder and oppositional defiant disorders (OR 2.4, 95% CI 1.4-4.4). The usefulness of mFTQ in measuring ND among adolescent inpatients is apparent. Therefore, it can be recommended to be used as a routine screening instrument for ND among adolescents hospitalized due to psychiatric disorders.
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- 2006
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7. [Smoking and attempted suicide among adolescent psychiatric patients].
- Author
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Mäkikyrö T, Hakko H, Ilomäki R, Läksy K, Räsänen P, Timonen M, Lappalainen J, and Marttunen M
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- Adolescent, Adolescent Behavior, Age Factors, Child, Cohort Studies, Comorbidity, Female, Finland epidemiology, Humans, Incidence, Male, Mental Disorders diagnosis, Risk Assessment, Sex Distribution, Survival Rate, Mental Disorders epidemiology, Smoking epidemiology, Suicide, Attempted statistics & numerical data
- Published
- 2004
8. The association of preceding traumatic brain injury with mental disorders, alcoholism and criminality: the Northern Finland 1966 Birth Cohort Study.
- Author
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Timonen M, Miettunen J, Hakko H, Zitting P, Veijola J, von Wendt L, and Räsänen P
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- Adolescent, Child, Cohort Studies, Diagnostic and Statistical Manual of Mental Disorders, Female, Finland epidemiology, Humans, International Classification of Diseases, Male, Mental Disorders diagnosis, Prospective Studies, Risk Factors, Alcoholism epidemiology, Brain Injuries epidemiology, Crime statistics & numerical data, Mental Disorders epidemiology
- Abstract
The purpose of this study was to test the hypothesis that traumatic brain injury (TBI) during childhood and adolescence is associated with psychiatric disorders, heavy alcohol use and criminal offenses in adulthood. We made use of an unselected, general population birth cohort (n=12058) in Northern Finland, which was followed up prospectively up to the age of 31. The data on TBIs of the cohort members were collected from the hospital case notes of the outpatient clinics of the hospitals in the region and from the Finnish Hospital Discharge Registers (FHDR). The data on mental disorders including alcohol diagnoses were also collected from the FHDR after a careful validation process. The Ministry of Justice provided information on criminal offenses for all subjects. The final number of subjects in our study was 5589 males and 5345 females. We found that after controlling for confounders, TBI during childhood or adolescence increased the risk of developing mental disorders two-fold (OR 2.1, 95% CI 1.1-3.6) and TBI was significantly related to later mental disorder with coexisting criminality in male cohort members (OR 4.1, 95% CI 1.2-13.6). The results support the TBI's association with psychiatric morbidity, which should not be overlooked when treating psychiatric patients, especially those with comorbid criminality.
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- 2002
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9. Risk of suicide related to income level in mental illness. Psychiatric disorders are more severe amount suicide victims of higher occupational level.
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Timonen M, Viilo K, Hakko H, Väisänen E, Räsänen P, and Särkioja T
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- Educational Status, Female, Finland epidemiology, Humans, Male, Prospective Studies, Socioeconomic Factors, Mental Disorders complications, Social Class, Suicide statistics & numerical data
- Published
- 2001
10. Psychiatric admissions at different levels of the national health care services and male criminality: the Northern Finland 1966 Birth Cohort study.
- Author
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Timonen M, Miettunen J, Hakko H, Järvelin MR, Veijola J, Kinnunen J, and Räsänen P
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- Adult, Catchment Area, Health, Cohort Studies, Finland epidemiology, Hospitalization, Humans, Male, Prospective Studies, Violence psychology, Crime, Mental Disorders epidemiology, Mental Disorders rehabilitation, Mental Health Services supply & distribution, Patient Admission statistics & numerical data
- Abstract
Background: It has earlier been suggested that one-third of violent offenders are recorded in psychiatric case registers. Our aim was to study whether violent and non-violent offenders differ with respect to admissions to any health care inpatient service due to psychiatric disorders., Methods: We used a genetically homogeneous, general population database from the Northern Finland 1966 Birth Cohort, together with the Finnish Hospital Discharge Register and national crime registers., Results: We found that one-third of violent and one-fourth of non-violent male offenders had at least one hospital admission due to a psychiatric disorder before the age of 32. Sixty-five violent criminals - 1.2% of all cohort males (n = 5636) - accounted for 14.4% of all psychiatric treatment days. The admission rates among both violent and non-violent male offenders were significantly higher when compared with males with no criminal history. Among violent males, only half (55.5%) of the inpatient hospital days due to psychiatric disorders occurred in psychiatric hospitals. The corresponding percentages for non-violent criminals and non-criminals were 64.9% and 74.1%, respectively. Among the violent offenders, one-third of hospital inpatient days occurred in university hospitals or central hospitals, and only 1.9% of them occurred in a comprehensive community care system., Conclusions: Violent offenders' admission rates due to a psychiatric diagnosis are high, and they are frequently treated at an inappropriate health care level.
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- 2000
- Full Text
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11. Comorbidities and mortality of hidradenitis suppurativa in Finland
- Author
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Tiri, H. (Hannu), Tasanen-Määttä, K. (Kaisa), Timonen, M. (Markku), and Huilaja, L. (Laura)
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kuolleisuus ,kasvaimet ,neevus ,lapsi ,neoplasms ,elämänlaatu ,cause of death ,mielenterveyshäiriöt ,suicide ,komorbiditeetti ,child ,märkivä hikirauhastulehdus ,nuori ,hidradenitis suppurativa ,patient care team ,psoriasis ,mortality ,mental disorders ,kuolinsyy ,comorbidity ,quality of life ,adolescent ,hoitotiimi ,life expectancy ,itsemurha ,elinajan odote ,nevus - Abstract
Hidradenitis suppurativa (HS) is a chronic inflammatory disease of hair follicles, characterized by subcutaneous inflammatory nodules and abscesses, typically on the axillary, genitofemoral, and perianal skin. Symptoms of HS, such as foul-smelling discharge from the inflamed lesions, pain, and disease location in sensitive areas, markedly diminish patients’ quality of life. Smoking and obesity are associated with HS, which also has several common comorbidities. While there is a growing body of evidence of somatic comorbidities in HS, psychiatric comorbidities have received less attention. Furthermore, literature on comorbidities in young patients with HS is scarce, and no systematic evaluation of mortality in HS has yet been undertaken. This study aimed to clarify the associations between HS and mental disorders, to explore both somatic and psychiatric comorbidities of HS in children and adolescents, and to determine the life expectancy and cause-specific risks of death in patients with HS. The study population comprised over 4300 cases with HS diagnosed in Finnish hospitals between 1987 and 2014. Age- and sex-matched patients with psoriasis and melanocytic nevi served as controls. Patient data were obtained from the statutory Finnish Care Register for Health Care. Information on dates and causes of death of the cases and controls were acquired from Statistics Finland. This study showed a heavy psychiatric disease burden in patients with HS. The prevalence rates and risks of all studied psychiatric comorbidities were higher in the HS than in the control groups. This was also evident in children and adolescents with HS, not only in adults. Furthermore, younger patients also had elevated risks for many somatic disorders including inflammatory bowel and joint diseases. Remarkably, the mean age at death in the HS group was only 60.5 years. The most common causes for death in the order of likelihood were: cardiovascular diseases, neoplasms, ‘accidents, suicides or violence’ and alcohol-related diseases. Suicide risk was elevated in women with HS. HS patients should be cautiously monitored for possible somatic and psychiatric comorbidities. It is clear that these patients require effective, comprehensive and multidisciplinary care to improve their quality of life and prevent premature death. Tiivistelmä Hidradenitis suppurativa (HS) on krooninen tulehduksellinen karvatuppien sairaus, joka heikentää elämänlaatua merkittävästi. Kivuliaat kyhmyt ja paiseet sekä vuotavat käytävät, jotka sijaitsevat useimmiten kainaloissa, nivusissa, genitaalialueella ja pakaravaossa, ovat sen tyypillisimpiä ilmenemismuotoja. HS-potilailla on moninaisia terveysongelmia, joita ovat mm. tupakointi, lihavuus ja suurentunut riski useisiin somaattisiin sairauksiin. Tutkimustieto HS-potilaiden psykiatrisista sairauksista on kuitenkin vähäistä eikä liitännäissairauksista lapsilla ole juuri lainkaan tietoa. Tämän lisäksi HS-potilaiden kuolemansyitä tai eliniänodotetta ei ole perusteellisesti selvitetty. Tällä tutkimuksella haluttiin määrittää psykiatristen sairauksien riski HS-potilailla ja selvittää sekä somaattisten että psykiatristen liitännäissairauksien todennäköisyyttä lapsuudessa ja nuoruudessa. Tarkoituksena oli myös tutkia, mihin sairauksiin HS-potilailla on suurentunut riski kuolla ja minkä ikäisinä he menehtyvät. Terveyden ja hyvinvoinnin laitoksen hoitoilmoitusjärjestelmästä etsittiin tiedot kaikista Suomen sairaaloissa vuosina 1987–2014 diagnosoiduista HS-tapauksisista (N=4381). Liitännäissairauksien tutkimista varten verrokeiksi valittiin psoriaasi- tai luomidiagnoosin saaneet henkilöt, jotka kaltaistettiin iän ja sukupuolen mukaan. Kuolintiedot menehtyneistä tutkimuspotilaista saatiin Tilastokeskukselta. HS-potilailla havaittiin selkeästi suurentunut psykiatristen sairauksien riski niin aikuisena kuin myös jo alle 18 vuoden iässä. Lisäksi monien somaattisten sairauksien, esim. tulehduksellisten suoli- ja nivelsairauksien, riski oli suurentunut lapsuudessa. HS-potilaiden todettiin menehtyvän huomattavan nuorella iällä, sillä heidän keskimääräinen elinikänsä oli vain 60,5 vuotta. Yleisimmät kuolinsyyt olivat sydän- ja verisuonitaudit, kasvaimet, ’onnettomuudet, itsemurhat ja väkivalta’ sekä alkoholiin liittyvät kuolemat. Itsemurhariski havaittiin suurentuneeksi naisilla. Tämän tutkimuksen perusteella HS-potilailla on runsaasti psykiatrisia liitännäissairauksia. Sekä somaattisten että psykiatristen sairauksien riski onkin pidettävä mielessä aina HS-potilaita hoidettaessa. Tehokas, kokonaisvaltainen ja moniammatillinen hoito on tärkeää potilaiden elämänlaadun parantamiseksi ja ennenaikaisen kuoleman ehkäisemiseksi.
- Published
- 2019
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