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Childhood sexual abuse (CSA) has been shown to predict the coupling of depression and inflammation in adulthood. Trust within intimate relationships, a core element in marital relations, has been shown to predict positive physical and mental health outcomes, but the mediating role of trust in partners in the association between CSA and inflammation in adulthood requires further study. The present study aimed to examine the impact of CSA on inflammatory biomarkers (IL-6 and IL-1β) in adults with depression and the mediating role of trust. A cross-sectional survey data set of adults presenting with mood and sleep disturbance was used in the analysis. CSA demonstrated a significant negative correlation with IL-6 level (r = -0.28, p<0. 01) in adults with clinically significant depression, while trust showed a significant positive correlation with IL-6 level (r = 0.36, p <.01). Sobel test and bootstrapping revealed a significant mediating role for trust between CSA and IL-6 level. CSA and trust in partners were revealed to have significant associations with IL-6 level in adulthood. Counterintuitively, the directions of association were not those expected. Trust played a mediating role between CSA and adulthood levels of IL-6. Plausible explanations for these counterintuitive findings are discussed. [ABSTRACT FROM AUTHOR]

The authors investigated sociodemographic predictors of the mental health status of college students ( N = 308) in Guam. Results indicated prevalence rates of 17.8%, 40.2%, and 25.6% for moderate or more severe levels of depression, anxiety, and stress, respectively. Psychological distress was found to be predicted by gender, ethnicity, living arrangement, and academic level. Comparisons with college students in the U.S. mainland and Hong Kong were also examined. Implications for counseling services and strategies are discussed. [ABSTRACT FROM AUTHOR]