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Start Over Descriptor "Antimetabolites, Antineoplastic standards" Topic methotrexate
2 results on '"Antimetabolites, Antineoplastic standards"'

1. Multicenter method evaluation of the ARK™ Methotrexate Immunoassay.

Author

Godefroid MJ, von Meyer A, Parsch H, Streichert T, Verstraete AG, and Stove V

Subjects
Antimetabolites, Antineoplastic standards, Antimetabolites, Antineoplastic therapeutic use, Calibration, Humans, Methotrexate standards, Methotrexate therapeutic use, Neoplasms drug therapy, Reagent Kits, Diagnostic, Antimetabolites, Antineoplastic blood, Immunoassay methods, Immunoassay standards, Methotrexate blood
Published
2014
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2. Revised FIGO staging system for gestational trophoblastic tumors. Recommendations regarding therapy.

Author

Goldstein DP, Zanten-Przybysz IV, Bernstein MR, and Berkowitz RS

Subjects
Antimetabolites, Antineoplastic administration & dosage, Antimetabolites, Antineoplastic standards, Female, Humans, Methotrexate administration & dosage, Methotrexate standards, Neoplasm Staging, Pregnancy, Prognosis, World Health Organization, Antimetabolites, Antineoplastic therapeutic use, Methotrexate therapeutic use, Trophoblastic Neoplasms drug therapy, Trophoblastic Neoplasms pathology, Uterine Neoplasms drug therapy, Uterine Neoplasms pathology
Abstract

Objective: To evaluate the revised International Federation of Gynecology and Obstetrics (FIGO) staging system for gestational trophoblastic tumors (GTT) and to recommend therapy., Study Design: Review of the literature regarding the development of the FIGO staging system, the World Health Organization (WHO) prognostic scoring system and Hammond's clinical classification for GTT plus analysis of response to single-agent chemotherapy in 546 patients treated at the New England Trophoblastic Disease Center., Results: The revised FIGO staging system appears to successfully combine anatomic staging and a prognostic clinical classification. The revised FIGO staging system reliably predicts treatment outcome and therefore can be used to help select optimal treatment protocols., Conclusion: The revised FIGO staging system is capable of predicting patients who respond poorly to single-agent chemotherapy, appears to reliably predict outcome and therefore can be used to help select appropriate treatment protocols.

Published
1998

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