1. Ganglion Cell and Retinal Nerve Fiver Layers Correlated with Time Disease of Bipolar Disorder Using 64 Cell Grid OCT Tool
- Author
-
Jose M. Larrosa, Luis E. Pablo, Elvira Orduna-Hospital, Elena García-Martín, Javier García-Campayo, Elisa Vilades, Yolanda López-Del-Hoyo, Vicente Polo, Maria Satue, and Beatriz Cordón
- Subjects
Adult ,Male ,Retinal Ganglion Cells ,0301 basic medicine ,medicine.medical_specialty ,Bipolar Disorder ,genetic structures ,Cell ,Posterior pole ,Degeneration (medical) ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,chemistry.chemical_compound ,Nerve Fibers ,0302 clinical medicine ,Retinal Diseases ,Optical coherence tomography ,Ophthalmology ,medicine ,Humans ,Bipolar disorder ,Ganglion cell layer ,Aged ,medicine.diagnostic_test ,business.industry ,Retinal ,Middle Aged ,medicine.disease ,eye diseases ,Sensory Systems ,Ganglion ,030104 developmental biology ,medicine.anatomical_structure ,chemistry ,030221 ophthalmology & optometry ,Female ,sense organs ,business ,Tomography, Optical Coherence - Abstract
Twenty-five eyes of 25 patients with bipolar disorder and 74 eyes of 74 healthy controls underwent retinal measurements of retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) thickness. Measurements were obtained using the Spectralis-OCT device with the new Posterior Pole protocol which assesses the macular area by analyzing retinal thickness in a grid of 64 (8*8) cells.Significant differences (Posterior Pole OCT protocol is a useful tool to assess changes in the inner retinal layers in bipolar disorder. These observed changes, especially those affecting the GCL, may be associated with disease evolution and may be predictive of the presence of the disease. OCT data could potentially be a useful tool for clinicians to diagnose and monitor BD patients.
- Published
- 2021