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This paper reports 414 cases of supratentorial ischemic cerebral infarcts diagnosed by CT. The clinical analysis was presented. CT value, specific changes in the CT pictures of the infarcts and ventricles were observed in accordance with the stages of the disorder. On the basis of these observations the development of the infarcts on CT can be divided into 4 stages. It is the first time that an latent stage of infarct has been mentioned. This stage is the time necessary for the pathological process to develop and cause the onset of changes in density. It is emphasized that negative CT in stroke not only can rule out the cerebral haemorrhage, but also should indicate the existence of the infarct, leading to the initiation of the treatment at extremely early stage.