Search

SCeAD affected predominantly a single artery (carotid, 870 patients [59.3%]; vertebral, 386 patients [26.3%]), whereas 212 patients (14.4%) had > 1 cervical artery involved. Dear Sirs, A recent hypothesis to explain the migraine-ischemic stroke (IS) association is that migraine might increase individual vulnerability to cerebral ischemia, making brain tissue more susceptible to ischemic injury [[1]]. Among migraine sufferers, we distinguished between "active migraine", which included participants with at least one self-reported migraine attack in the year preceding the baseline evaluation, and "prior (non-active) migraine", which included those who reported ever having had migraine but no attack in the year preceding the baseline evaluation. Actually, if the above is true, one would expect a higher prevalence of migraine and, possibly, migraine activity, among sCeAD patients who develop IS than among those who do not, as well as an association of migraine with sCeAD only or more prominent in the subgroup of patients with IS as disease manifestation compared to non-sCeAD subjects. [Extracted from the article]

The available evidence on the relationship between migraine and cryptogenic ischemic stroke (CIS) is scarce. Thirty-six cases had missing data in the variable "any migraine"; 70 participants (58 cases and 12 control subjects) had missing data in the variables "migraine without aura" and "migraine with aura.". [Extracted from the article]