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Cow's milk allergy is the most common food allergy among children. Patients with cow's milk allergy may present a wide range of complaints. Complaints can occur in multiple organ systems. The gold standard to confirm a diagnosis of cow's milk allergy is the double-blind placebo-controlled food challenge. The treatment consists of the elimination of cow's milk from a child's diet.It is estimated that at the age of 1 year, 75% of children with cow's milkallergy have become tolerant to cow's milk, and 90% at the age of 4 years. It is recommended to expose all infants with cow's milk allergy to cow's milk at the age of 1 year to see if they have become tolerant.