It is essential that precipitation of asphaltenes is recognized early in the planning stage of any CO2 enhanced oil recovery (EOR) project so that appropriate testing can be performed to evaluate whether there will be a negative impact on reservoir performance. This article presents detailed evaluations of slim tube data that were obtained during CO2 injection using a medium-gravity Iranian crude oil. A crude oil from Bangestan reservoir of Ahwaz oilfield containing 18.2% asphaltenes with ~31.5 °API gravity was flooded by purified CO2 (>96% CO2) in a slim tube apparatus under 2,700 psi at 110°C. We were going to determine the minimum miscibility pressure (MMP) of the sample oil under injection of CO2 flood, but when a CO2 slim tube test was performed for this oil at 2,700 psi, less than half of the saturated oil in the tube was recovered, which implied that the displacement process was immiscible. At this pressure, the asphaltene deposition in the slim tube apparatus was so severe that even a pressure gradient of 6,200 lb/in2 was not able to displace any fluid through the capillary tube. Therefore, we abandoned MMP determination with this sample and investigated the problem. Due to the high percentage of asphaltenes in the sample, using the slim tube MMP as an apparatus for determining minimum miscibility pressure of CO2 and sample oil can be misleading. [ABSTRACT FROM AUTHOR]