1. Molecular epidemiology of asymptomatic bacteriuria in the elderly.
- Author
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Rahav G, Pinco E, Bachrach G, and Bercovier H
- Subjects
- Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Genotype, Geriatric Assessment statistics & numerical data, Homes for the Aged statistics & numerical data, Humans, Israel epidemiology, Male, Microbial Sensitivity Tests, Nursing Homes statistics & numerical data, Phenotype, Polymorphism, Restriction Fragment Length, Ribotyping, Bacteriuria epidemiology, Bacteriuria genetics, Escherichia coli genetics, Escherichia coli Infections epidemiology, Escherichia coli Infections genetics, Molecular Epidemiology
- Abstract
Objectives: to determine the incidence and the dynamics of asymptomatic bacteriuria in ambulatory nursing home residents, and to characterise bacteria according to their phenotype and genotype., Design: an 18 months prospective longitudinal study., Subjects: 42 nursing home residents (31 female, 11 males) without indwelling catheters., Methods: urine was sampled every 3 months. Antibiograms, biotyping and ribotyping were performed., Results: the cumulative percent of infection for females and males was 75% and 27% respectively. Osteoporosis was associated with bacteriuria. Ribotypes of consecutive Escherichia coli isolates indicated that each patient harboured a different strain., Conclusions: asymptomatic bacteriuria in the elderly is a dynamic and transient phenomenon. Osteoporosis is common among this population. Ribotyping is a powerful tool in the elucidation of the epidemiology of this bacteriuria.
- Published
- 2003
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