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Your search keyword '"Julio César González Aguilera"' showing total 5 results
Start Over Author "Julio César González Aguilera" Topic mortalidad
5 results on '"Julio César González Aguilera"'

1. Design and validation of a prognostic index of death from COVID-19: a prospective cohort

Author

Alexis Álvarez Aliaga, Julio César González Aguilera, Alexis Suárez Quesada, Andrés José Quesada Vázquez, Liannys Lidia Naranjo Flores, and Adonis Frómeta Guerra

Subjects
covid-19, factores pronósticos, índice pronóstico, mortalidad, Medicine (General), R5-920, Public aspects of medicine, RA1-1270
Abstract

Introduction: COVID-19 caused high morbidity and mortality worldwide due to the lack of effective treatment and timely recognition of individuals with worse prognosis. Objective: To evaluate the capacity of the index to predict the risk of death in patients with covid-19, based on prognostic factors. Material and Methods: An analytical cohort study was carried out in patients with COVID-19 in the General Provincial Hospital "Carlos Manuel de Céspedes" of Bayamo municipality, Granma province, from January 1, 2020 to March 31, 2023. Results: Internal validity of the index was adequate with a sensitivity of 88.96%, specificity of 92.58% and a validity index of 91.22%. The discriminative capacity of the index (area under the ROC curve of 0.975) and the calibration (Hosmer and Lemeshow: p= 0.383) were appropriate. Conclusions: The predictive capacity and calibration of the index were adequate, as well as the accuracy and reliability, so it can be used as a clinical surveillance tool.

Published
2024

2. Prognostic model for death from COVID-19

Author

Alexis Álvarez Aliaga, Julio César González Aguilera, Alexis Suárez Quesada, Andrés José Quesada Vázquez, and Liannys Lidia Naranjo Flores

Subjects
covid-19, factores pronósticos, modelos pronósticos, mortalidad, Medicine (General), R5-920, Public aspects of medicine, RA1-1270
Abstract

Introduction: Tools have been used to predict the risk of COVID-19, but none have evaluated their external validity. Objective: To evaluate the capacity of a model, based on prognostic factors, to predict the risk of dying from COVID-19. Material and Methods: A cohort analytical study was carried out on patients with COVID-19 at the “Carlos Manuel de Céspedes” provincial general hospital in the Bayamo municipality, province of Granma, from January 1st, 2020 to March 31st, 2023. Confirmed COVID-19 patients were selected. Death was defined as the dependent variable and sociodemographic variables were considered as independent variables for evaluation, including: toxic habits, comorbidity, biomarkers, phenotypes, and prognostic scales. Results: The Cox proportional regression model demonstrated that the factors associated with the prognosis of death were: classifying phenotype 5 (HR= 6.41; 95% CI= 1.49 to 13.44; p= 0.015); history of arterial hypertension (HR= 2.01; 95% CI= 1.34 to 2.98; p= 0.001); and the RALE scale at 4 or more points (HR= 1.94; 95% CI=1, 47 to 7.90; p= 0.047). The discriminative capacity of the model (C statistic = 0.891) and its calibration were adequate (X2 = 5.384; p = 0.637). Conclusions: The predictive capacity and calibration of the model were adequate. The model can be used as a clinical and epidemiological surveillance instrument, by staging the risk of dying in the most vulnerable subjects.

Published
2024

3. Clinical, epidemiological and therapeutic characteristics in patients treated in the intensive care unit

Author

Julio César González Aguilera, Víctor Manuel Leyva Lorenzo, Yoleinis Esperanza Vázquez Belizón, Armando Arias Ortiz, and Jorge Omar Cabrera Lavernia

Subjects
epidemiología, factores de riesgo, terapéutica, mortalidad, paciente crítico, unidad de cuidados intensivos., Medicine, Medicine (General), R5-920
Abstract

Introduction: Data of characteristics of critically ill patients generally come from of European countries. Objective: To identify the clinical, epidemiological and therapeutic characteristics of patients treated in the intensive care unit. Methods: An observational, prospective study was carried out in the intensive care unit, in periods of the years 2018, 2019 and 2020. Patients admitted for more than 24 hours were included. The variables age, sex, origin and diagnosis of the patients, degree of severity, risk factors, community infections and those associated with health care were defined. Results: The patient's average age was 38.6 years (36.1-46.3) and 61.0 % belonged to female. APACHE II mean value and standard deviation was 8.9+6.4 and 1,2 + 2.1 for SOFA. Mortality was 7.0 %. Hypoalbuminemia (24.5 %) were the most important risk factor; 27.3 % of patients received a central venous catheter and 13.9 % mechanical ventilation. Community infections were developed by 54.0% of patients and 8.0 % acquired healthcare associated infections. Conclusions: The population it is characterized by being close to fourth decade, belonging to female sex, proceeding from operating room, clinical conditions, hypoalbuminemia and low values of APACHE II and SOFA scores. Mortality remains stable and the incidence of community infections is high.

Published
2021

4. Características epidemiológicas y clínicas en pacientes con diagnóstico de pancreatitis aguda en la Unidad de Cuidados Intensivos

Author

Rafael Ernesto Díaz Masó, Julio César González Aguilera, Ariatna Guerra Fonseca, Jorge Omar Cabrera Lavernia, Gloria Mabel Martí Garcés, and Luis Antonio Algas Hechavarría

Subjects
lcsh:R5-920, unidad de cuidados intensivos, lcsh:Public aspects of medicine, pancreatitis, mortalidad, morbilidad, lcsh:RA1-1270, lcsh:Medicine (General)
Abstract

RESUMEN Se desarrolló un estudio descriptivo, transversal y prospectivo con el objetivo de caracterizar desde el punto de vista epidemiológico y clínico a los pacientes con pancreatitis aguda en la Unidad de Cuidados Intensivos del hospital general universitario Carlos M. de Céspedes de Bayamo, Granma, Cuba, en el período comprendido desde el primero de febrero de 2015 hasta el 30 de septiembre de 2017. Se incluyeron 42 pacientes que cumplieron los criterios para el diagnóstico de la enfermedad. La pancreatitis aguda representó el 2,9 % de los ingresos y predominó en el grupo de edad 542 de 46 a 60 años (33,3 %). El 54,8 % de los pacientes pertenecieron al sexo femenino; y la raza negra/mestiza (69,0 %), el hábito de fumar (33,3 %) y la obesidad (28,5 %) se identificaron como los factores predisponentes más importantes. El 71,4 % de los enfermos tuvieron causa biliar y el 52,4 % una pancreatitis aguda leve; el perfil morfológico más frecuente fue la necrosis pancreática (50,0 %). El fallo orgánico transitorio se presentó en el 26,2 % de los pacientes y el persistente en el 21,4 %. La mortalidad fue de 16,7 %. De los pacientes que presentaron una forma grave de pancreatitis aguda el 77,8 % falleció; en aquellos con fallo orgánico se produjo la muerte en el 35,0 % y en el 33,0 % de los que desarrollaron una necrosis pancreática. El 100 % de los fallecidos tuvieron una forma grave de la enfermedad, fallo de órganos y necrosis pancreática. ABSTRACT A descriptive, cross-sectional and prospective study was developed with the objective of characterizing patients with acute pancreatitis from an epidemiological and clinical point of view in the Intensive Care Unit at the general university hospital Carlos Manuel de Cespedes, Bayamo municipality, Granma province, Cuba, from February 1, 2015 to September 30, 2017. Forty-two patients who met the criteria for diagnosis of the disease were included. Acute pancreatitis accounted for 2.9 % from all admissions and predominated in the age group of 46 to 60 years (33.3 %); 54.8 % of the patients were female; and the black/half-breed race (69.0 %), the smoking habit (33.3 %) and obesity (28.5 %) were identified as the most important predisposing factors; 71.4 % of patients had biliary causes and 52.4 % had mild acute pancreatitis; the most frequent morphological profile was pancreatic necrosis (50.0 %). Transient organ failure occurred in 26.2 % of patients and persistent failure in 21.4 %. The mortality was 16.7 %. Of the patients who presented a severe form of acute pancreatitis, 77.8 % died; in those with organ failure, death occurred in 35.0 % and in 33.0 % of those who developed pancreatic necrosis; 100 % of the deceased had a severe form of the disease, organ failure and pancreatic necrosis.

Published
2018

5. Incidencia y consecuencias de la traqueobronquitis asociada a ventilación mecánica en unidades de cuidados intensivos Incidence and consequences of tracheobronchitis associated with ventilator in ICUs

Author

Anselmo Abdo Cuza, Roberto Castellanos-Gutiérrez, Julio César González-Aguilera, Reinaldo Reyes-Tornés, Yoleinis Vázquez-Belizón, Manuel Ernesto Somoza-García, Javier Casas-Rodríguez, Anabel Barani-Larrazabal, Adriel Viera-Paz, Alejandro Vázquez-Soto, Abel Corcho-Martínez, Carlos Roberto Valdés-Riñak, Bárbara Reigoso-Cruz, Lissette del Rosario López-González, Daysi Eduarda Álvarez-Montalvo, Janet Moreira-Barrios, José Núñez-Wong, Odalys Marrero-Martínez, Manuel Lescay-Cantero, Armando Pardo-Núñez, Geidy Leal-Alpizar, Alain Cueto-Medina, Namibia Espinosa-Nodarse, and Maykel Rocha-Quintana

Subjects
hospital infections, infección relacionada con el cuidados sanitario, neumonía asociada a ventilación mecánica, lcsh:R, infección nosocomial, lcsh:Medicine, ventilator-associated tracheobronchitis, mortality, infección intrahospitalaria, ventilator-associated pneumonia, traqueobronquitis asociada a ventilación mecánica, nosocomial infection, ICU, mortalidad, Unidad de Cuidados Intensivos, health care-related infection
Abstract

Introducción: las infecciones respiratorias bajas ocupan el primer lugar entre las infecciones relacionadas con el cuidado sanitario en unidades de cuidados intensivos. Objetivos: describir la incidencia y las consecuencias, sobre estadía y mortalidad, de la traqueobronquitis asociada a ventilación mecánica (TAVM) en UCI. Métodos: estudio multricéntrico, descriptivo, prospectivo y transversal, en 6 UCI de adultos. Se estudiaron 454 pacientes. Las variables de estudio fueron recogidas en 2 bases de datos. Resultados: tasa de incidencia de TAVM: 1,76 %. Con respecto al número total de pacientes con factor de riesgo: 6,06 %. Densidad de incidencia: 7,61 ‰ por 1 000 d con factor de riesgo. Estadía media, TAVM: 13,13 d, pacientes sin IRCS: 5,49 d (p=0,006). Mortalidad, TAVM: 25 %, NAVM: 55,2 %, pacientes sin IRCS: 14,9 % (p=0,000). Conclusiones: la TAVM no es infrecuente en UCI. Su diagnóstico implica aumento de estadía y mortalidad en pacientes ventilados. Se justifica la implementación de medidas de vigilancia y prevención.Introduction: lower respiratory infections rank first among related infections in health care intensive care units. Objectives: to describe the incidence and consequences of stay and mortality of ventilator-associated tracheobronchitis (TAVM) in ICU. Methods: a multicenter, descriptive, prospective and cross-sectional study was conducted in 6 adult ICU. 454 patients were studied. The study variables were collected in two databases. Results: TAVM incidence rate: 1.76 %, relative to the total number of patients with risk factor: 6.06 %. Incidence density: 7.61 % by 1000 d with risk factor. Average stay, TAVM: 13.13 d, patients without IRCS: 5.49 d (p = 0.006). Mortality, TAVM: 25 %, VAP: 55.2 %, patients without IRCS: 14.9 % (p = 0.000). Conclusions: TAVM is not uncommon in ICU. Its diagnosis involves increased stay and its mortality in ventilated patients. The implementation of surveillance and prevention measures is requiered.

Published
2013

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