1. Determinants of mortality among hospitalized patients with COVID-19 during first and second waves of the pandemic: A retrospective cohort study from an isolation center in Kano, Nigeria
- Author
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Farouq Muhammad Dayyab, Hussain Abdullahi Bashir, Abdulwahab Kabir Sulaiman, Garba Iliyasu, Muhammad Hamza, Ahmad Maifada Yakasai, Ibrahim Nashabaru, Hadiza Saidu, Bashir Garba Ahmad, Bashir Dabo, Aminu Yusuf Abubakar, Ibrahim Musa Idris, Abdulrauf Sani Yahaya, Mustapha Ado, Ibrahim Sabo Abdurrahman, Hafizu Musa Usman, Mohammed Kabiru Bello, Jaafar Suleiman Jaafar, Anifowose Abdullahi, Abubakar Muhammad Alhassan, Abdulmalik Ahmad, Alika Ehima Allen, Medu Oghenekevwe Ezekiel, Muhammad Abdullahi Umar, Muhammad B. Abdullahi, Sahabi Kabir Sulaiman, Tijjani Hussaini, Amina Abdullahi Umar, Aminu Ibrahim Tsanyawa, Sabitu Y. Shuaibu, Nasir Alhassan Kabo, Basheer Lawan Muhammad, Mohammed Nura Yahaya, Imam Wada Bello, Ashiru Rajab, Abdulhakim Muhammad Daiyab, Aminu Faruk Kabara, Muhammad Sule Garko, and Abdulrazaq Garba Habib
- Subjects
Multidisciplinary - Abstract
BackgroundCoronavirus disease 2019 (COVID-19) has emerged as an important cause of morbidity and mortality worldwide.The aim of this study is to identify the clinical predictors of mortality among patients with COVID-19 pneumonia during first and second waves in a treatment center in northwestern Nigeria.MethodsThis was a retrospective cohort study of 195 patients hospitalized with COVID-19 between April 2020 to March 2021 at a designated COVID-19 isolation center in Kano State, Northwest Nigeria. Data were summarized using frequencies and percentages. Unadjusted odds ratios and 95% confidence intervals and p-values were obtained. To determine independent determinants of mortality, we performed a stepwise multivariate logistic regression model.ResultsOf 195 patients studied, 21(10.77%) patients died. Males comprised 158 (81.03%) of the study population. In the adjusted stepwise logistic regression analysis, age>64 years (OR = 9.476, 95% CI: 2.181–41.165), second wave of the pandemic (OR = 49.340, 95% CI:6.222–391.247), cardiac complications (OR = 24.984, 95% CI: 3.618–172.508), hypertension (OR = 5.831, 95% CI:1.413–24.065) and lowest systolic blood pressure while on admission greater than or equal to 90mmHg were independent predictors of mortality (OR = 0.111, 95%CI: 0.021–0.581).ConclusionStrategies targeted to prioritize needed care to patients with identified factors that predict mortality might improve patient outcome.
- Published
- 2023