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I Editor i Polyarteritis nodosa (PN) causes systemic vasculitis in the small- to medium-sized arteries, which sometimes invades the central nervous system (CNS).[1] Multiple sclerosis (MS) is an immune-mediated demyelinating disorder of the CNS. In addition, double inversion recovery sequence clearly revealed multiple juxta-cortical lesions (Fig. c) and susceptibility-weighted imaging (SWI) showed intramedullary veins penetrating through some of the lesions (Fig. d), both compatible with MS.[[3]] Cerebrospinal fluid was positive in oligoclonal band. Human leucocyte antigen typing revealed the presence of DRB1*04:05, which is the susceptible allele for MS.[5] Collectively, we concluded that these CNS lesions are indicative of MS. [Extracted from the article]