1. Determination of viable myocardium through delayed enhancement cardiac magnetic resonance imaging combined with 18 F-FDG PET myocardial perfusion/metabolic imaging before CABG.
- Author
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Xu D, Zhang J, Liu B, Fu D, Li J, and Fan L
- Subjects
- Humans, Male, Female, Middle Aged, Aged, Time Factors, Treatment Outcome, Recovery of Function, Stroke Volume, Reproducibility of Results, Myocardial Stunning diagnostic imaging, Myocardial Stunning physiopathology, Myocardial Stunning etiology, Multimodal Imaging, Magnetic Resonance Imaging, Myocardial Contraction, Coronary Circulation, Retrospective Studies, Predictive Value of Tests, Coronary Artery Bypass, Fluorodeoxyglucose F18 administration & dosage, Myocardium pathology, Tissue Survival, Radiopharmaceuticals administration & dosage, Positron-Emission Tomography, Myocardial Perfusion Imaging methods, Ventricular Function, Left, Coronary Artery Disease diagnostic imaging, Coronary Artery Disease physiopathology, Coronary Artery Disease surgery, Coronary Artery Disease therapy
- Abstract
Purpose: Study aims to investigate the consistency of delayed enhancement cardiac magnetic resonance imaging (DE-CMR) and
18 F-FDG PET myocardial imaging in evaluating myocardial viability before CABG., Methods: The study analyzed data from 100 patients who were examined with DE-CMR, PET imaging, and echocardiography before and after CABG. All subjects were followed up for 6-12 month post- CABG., Results: DE-CMR and PET imaging have high consistency (90.1%; Kappa value = 0.71, p < 0.01) in determining myocardial viability. The degree of delayed enhancement was negatively correlated with the improvement in myocardial contractile function in this segment after revascularization (P < 0.001). The ratio of scarred myocardial segments and total DE score was significantly lower in the improvement group than non-improvement group. Multivariate regression identified that hibernating myocardium (OR = 1.229, 95%CI: 1.053-1.433, p = 0.009) was influencing factor of LVEF improvement after CABG., Conclusion: Both imaging techniques are consistent in evaluating myocardial viability. Detecting the number of hibernating myocardium by PET is also important to predict the left heart function improvement after CABG., (© 2024. The Author(s).)- Published
- 2024
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