1. Synthesis of nano-bowls with a Janus template
- Author
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Mo, Alexander H, Landon, Preston B, Emerson, Chris D, Zhang, Chen, Anzenberg, Paula, Akkiraju, Siddhartha, and Lal, Ratnesh
- Subjects
Macromolecular and Materials Chemistry ,Engineering ,Chemical Sciences ,Nanotechnology ,Bioengineering ,Carboxylic Acids ,Nanoparticles ,Nanostructures ,Particle Size ,Polystyrenes ,Silicon Dioxide ,Solvents ,Surface Properties ,Physical Sciences ,Technology ,Nanoscience & Nanotechnology ,Chemical sciences ,Physical sciences - Abstract
Colloidal particles with two or more different surface properties (Janus particles) are of interest in catalysis, biological imaging, and drug delivery. Eccentric nanoparticles are a type of Janus particle consisting of a shell that envelops the majority of a core particle, leaving a portion of the core surface exposed. Previous work to synthesize eccentric nanoparticles from silica and polystyrene have only used microemulsion techniques. In contrast we report the sol-gel synthesis of eccentric Janus nanoparticles composed of a silica shell around a carboxylate-modified polystyrene core (Janus templates). In addition, we have synthesized nano-bowl-like structures after the removal of the polystyrene core by organic solvent. These Janus templates and nanobowls can be used as a versatile platform for site-specific functionalization or controlled theranostic delivery.
- Published
- 2015