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Hydrogen peroxide (H2O2) is one of the intermediates or final products of biological metabolism and participates in many important biological processes of life activities. The detection of H2O2 is of great significance in clinical disease monitoring, environmental protection, and bioanalysis. In this study, Ti3C2-based nanohybrids are prepared by the biological modification and self-assembled peptide nanosheets (PNSs)-based biomimetic synthesis of copper sulfide nanoparticles (CuS NPs), which show potential application in the fabrication of low-cost and high-performance electrochemical H2O2 biosensors. The synthesized CuS-PNSs/Ti3C2 nanohybrids exhibit excellent electrochemical performance towards H2O2, in which CuS NPs can catalyze the decomposition of H2O2 and realize the transformation from a chemical signal to an electrical signal to achieve the purpose of H2O2 detection. The prepared CuS-PNSs/Ti3C2-based electrochemical biosensor platform exhibits a wide detection range (5 μM–15 mM) and a low detection limit (0.226 μM). In addition, it reveals good selectivity and stability and can realize the monitoring of H2O2 in a complex environment. The successful biomimetic synthesis of CuS-PNSs/Ti3C2 hybrid nanomaterials provides a green and friendly strategy for the design and synthesis of functional nanomaterials and also provides a new inspiration for the construction of highly effective electrochemical biosensors for practical detection of H2O2 in various environments. [ABSTRACT FROM AUTHOR]

Nanomaterial-based phototherapy has become an important research direction for cancer therapy, but it still to face some obstacles, such as the toxic side effects and low target specificity. The biomimetic synthesis of nanomaterials using biomolecules is a potential strategy to improve photothermal therapy (PTT) and photodynamic therapy (PDT) techniques due to their endowed biocompatibility, degradability, low toxicity, and specific targeting. This review presents recent advances in the biomolecule-mimetic synthesis of functional nanomaterials for PTT and PDT of cancers. First, we introduce four biomimetic synthesis methods via some case studies and discuss the advantages of each method. Then, we introduce the synthesis of nanomaterials using some biomolecules such as DNA, RNA, protein, peptide, polydopamine, and others, and discuss in detail how to regulate the structure and functions of the obtained biomimetic nanomaterials. Finally, potential applications of biomimetic nanomaterials for both PTT and PDT of cancers are demonstrated and discussed. We believe that this work is valuable for readers to understand the mechanisms of biomimetic synthesis and nanomaterial-based phototherapy techniques, and will contribute to bridging nanotechnology and biomedicine to realize novel highly effective cancer therapies. [ABSTRACT FROM AUTHOR]

Metal oxide nanoparticles have been widely utilized for the fabrication of functional gas sensors to determine various flammable, explosive, toxic, and harmful gases due to their advantages of low cost, fast response, and high sensitivity. However, metal oxide-based gas sensors reveal the shortcomings of high operating temperature, high power requirement, and low selectivity, which limited their rapid development in the fabrication of high-performance gas sensors. The combination of metal oxides with two-dimensional (2D) nanomaterials to construct a heterostructure can hybridize the advantages of each other and overcome their respective shortcomings, thereby improving the sensing performance of the fabricated gas sensors. In this review, we present recent advances in the fabrication of metal oxide-, 2D nanomaterials-, as well as 2D material/metal oxide composite-based gas sensors with highly sensitive and selective functions. To achieve this aim, we firstly introduce the working principles of various gas sensors, and then discuss the factors that could affect the sensitivity of gas sensors. After that, a lot of cases on the fabrication of gas sensors by using metal oxides, 2D materials, and 2D material/metal oxide composites are demonstrated. Finally, we summarize the current development and discuss potential research directions in this promising topic. We believe in this work is helpful for the readers in multidiscipline research fields like materials science, nanotechnology, chemical engineering, environmental science, and other related aspects. [ABSTRACT FROM AUTHOR]

• Self-assembly mechanism and function regulation of peptide nanomaterials are disscussed. • Combination strategies of peptide nanomaterials with other nanomaterials are summeried. • Construction of peptide-based hybrid nanomaterials for biomedical applications are described. • Functional refinement, computer simulation and pespectives of peptide materials are presented. Molecular design and biomimetic/bioinspired synthesis provide facile ways for the construction of functional nanomaterials for various applications. Peptide-based functional nanomaterials with ideal morphology and functions can be obtained through the design of peptide sequences, regulation of molecular self-assembly, biomimetic synthesis, and hybridization with other functional nanoscale building blocks. In this review, we present a progress report on the combination of peptide self-assembly and biomimetic synthesis for tailoring the structure and functions of peptide nanomaterials aiming to biomedical applications. Through structural and functional tailoring, peptide-based nanomaterials exhibit enhanced chemical, physical, and biological properties, which greatly promote their potential applications in biomedical fields, including biosensors, bioimaging, photothermal/photodynamic therapy, tissue engineering, drug/gene delivery, and antibacterial materials. This interesting research topic could be promoted by discovering more peptide sequences, investigating the self-assembly behavior of peptides, simulating the internal driving factors of peptide self-assembly, and accurately controlling the functions of peptides to prepare peptide-based hybrid nanomaterials, which are beneficial to design and fabricate functional biocompatible nanosystems for clinical biomedicine. [ABSTRACT FROM AUTHOR]

High-performance but low-cost structural materials with nanoscale precipitations are vitally important for engineering applications in advanced industry systems. Thus far, the classical nucleation mechanism assumes a critical nucleus of a homogeneous composition up to a sharp boundary with a large energy barrier of nucleation. A fine dispersion of nanoscale precipitates often requires strong solute supersaturations with expensive alloying additions or otherwise deteriorated strength-ductility, weldability, and fabricability. The simultaneous satisfaction of all these mutually exclusive requirements is the longstanding issue for the design of advanced materials for structural applications. In this alloy design, we have adopted a revolutionary approach of ultra-strong iron-based alloys that have resolved all these key issues through non-classical nanoscale precipitations and multi-elemental partitioning. Such an alloy design strategy offers a unique approach to control nanoscale precipitates with low solute supersaturations. Fine precipitations so designed lead to the strong enhancement of both the precipitate-dislocation interactions and work-hardening capacity, resulting with a sharp increase of the yield strength (YS) to as high as 1500 MPa and tensile ductility up to 15%. Furthermore, our design assures outstanding fabricability together with superior post-weld properties through dense nanoscale reprecipitations (∼1024 m −3) in a well economical manner for production. The non-classical actions unfold brand new pathways for precipitation of various intermediate structures and chemistries with low energy barriers, especially useful for the design of sustainable and economical modern alloy systems. (a) The all-in-one ultra-strong iron-based alloy design through careful non-classical nanoscale multi-elemental partitioning and precipitate nucleation controls. Such a strategy turns the embrittling equilibrium precipitates at grain boundaries to fine dispersion of nanoscale multi-component precipitates, especially important in advanced alloy designs with low solute supersaturations. (b) The outstanding mechanical properties of our all-in-one ultra-strong iron-based alloys. (c) Our all-in-one ultra-strong alloys outperform other high-specific strength alloy systems such as Ti-6Al-4 V and Al 7075. A significant cost reduction of our alloys by more than 90% in comparison with the conventional ordered intermetallic strengthened steel alloys, Marage 200 for instance. (d) The superb post-weld mechanical performances with zero strength loss of our alloys due to nano-reprecipitations. [Display omitted] [ABSTRACT FROM AUTHOR]

Due to the good biocompatibility and flexibility of cellulose and the excellent optical, electronic, as well as mechanical properties of carbon nanomaterials (CNMs), cellulose/CNM hybrid materials have been widely synthesized and used in energy storage, sensors, adsorption, biomedicine, and many other fields. In this review, we present recent advances (2016-current) in the design, structural design, functional tailoring and various applications of cellulose/CNM hybrid materials. For this aim, first the interactions between cellulose and CNMs for promoting the formation of cellulose/CNM materials are analyzed, and then the hybridization between cellulose with various CNMs for tailoring the structures and functions of hybrid materials is introduced. Further, abundant applications of cellulose/CNM hybrid materials in various fields are presented and discussed. This comprehensive review will be helpful for readers to understand the functional design and facile synthesis of cellulose-based nanocomposites, and to promote the high-performance utilization and sustainability of biomass materials in the future. The study on the interactions between cellulose and carbon nanomaterials promote the structural design, functional tailoring, and advanced applications of their hybrid materials. [Display omitted] [ABSTRACT FROM AUTHOR]

In this paper, we report a chemiluminescence (CL) sensor array based on catalytic nanomaterials for the discrimination of ten sweeteners, including five natural sugars and five artificial sweeteners. The CL response patterns ('fingerprints') can be obtained for a given compound on the nanomaterial array and then identified through linear discriminant analysis (LDA). Moreover, each pure sweetener was quantified based on the emission intensities of selected sensor elements. The linear ranges for these sweeteners lie within 0.05-100 mM, but vary with the type of sweetener. The applicability of this array to real-life samples was demonstrated by applying it to various beverages, and the results showed that the sensor array possesses excellent discrimination power and reversibility. [Figure not available: see fulltext.] [ABSTRACT FROM AUTHOR]