1. The natverse, a versatile toolbox for combining and analysing neuroanatomical data.
- Author
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Bates AS, Manton JD, Jagannathan SR, Costa M, Schlegel P, Rohlfing T, and Jefferis GS
- Subjects
- Animals, Drosophila, Humans, Neurons physiology, Connectome methods, Image Interpretation, Computer-Assisted methods, Neuroanatomy methods, Software
- Abstract
To analyse neuron data at scale, neuroscientists expend substantial effort reading documentation, installing dependencies and moving between analysis and visualisation environments. To facilitate this, we have developed a suite of interoperable open-source R packages called the
natverse . Thenatverse allows users to read local and remote data, perform popular analyses including visualisation and clustering and graph-theoretic analysis of neuronal branching. Unlike most tools, thenatverse enables comparison across many neurons of morphology and connectivity after imaging or co-registration within a common template space. Thenatverse also enables transformations between different template spaces and imaging modalities. We demonstrate tools that integrate the vast majority of Drosophila neuroanatomical light microscopy and electron microscopy connectomic datasets. Thenatverse is an easy-to-use environment for neuroscientists to solve complex, large-scale analysis challenges as well as an open platform to create new code and packages to share with the community., Competing Interests: AB, JM, SJ, MC, PS, TR, GJ No competing interests declared, (© 2020, Bates et al.)- Published
- 2020
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