1. Production of the PET isotope 11 C in hadron therapy via neutron knockout.
- Author
-
Simpson EC
- Subjects
- Carbon Radioisotopes, Elementary Particles therapeutic use, Neutrons, Positron-Emission Tomography
- Abstract
Purpose: Positron emitting isotopes such as
11 C and10 C can be used for vital dose verification in hadron therapy. These isotopes are produced when the high energy12 C primary beam particles undergo nuclear reactions within the patient., Methods: We discuss a model for calculating cross sections for the production11 C in12 C+12 C collisions, applicable at hadron therapy energies., Results: Good agreement with the available cross section measurements is found for12 C(-1n), though more detailed, systematic measurements would be very valuable., Conclusions: Nuclear structure plays a crucial role in the reactions of light nuclei, particularly when those reactions are peripheral and involve only a few nucleons. For such reactions, nuclear structure has a strong influence on the energy and angular distribution of the cross section, and is an important consideration for reliable dose verification using11 C in hadron therapy., (Copyright © 2016. Published by Elsevier Ltd.)- Published
- 2016
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