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Your search keyword '"Rofecoxib -- Evaluation"' showing total 4 results
Start Over Descriptor "Rofecoxib -- Evaluation" Topic nonsteroidal anti-inflammatory drugs -- evaluation
4 results on '"Rofecoxib -- Evaluation"'

1. Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial

Author

Aisen, Paul S., Schafer, Kimberly A., Grundman, Michael, Pfeiffer, Eric, Sano, Mary, Davis, Kenneth L., Farlow, Martin R., Jin, Shelia, Thomas, Ronald G., and Thal, Leon J.

Subjects
Alzheimer's disease -- Development and progression, Nonsteroidal anti-inflammatory drugs -- Evaluation, Rofecoxib -- Evaluation, Naproxen -- Evaluation
Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) may not slow the progression of Alzheimer's disease, according to a study of 351 patients. The drugs also had serious side effects, including gastrointestinal bleeding, stroke, and heart attack. This study was started because research has shown that chronic inflammation in the brain may cause Alzheimer's disease.

Published
2003

2. Rofecoxib may cut risk of lower GI bleeding by 54%: compared with naproxen in study of more than 8,000 rheumatoid arthritis patients. (First Prospective Clinical Trial)

Author

Jancin, Bruce

Subjects
Rofecoxib -- Evaluation, Rofecoxib -- Physiological aspects, Naproxen -- Evaluation, Naproxen -- Physiological aspects, Gastrointestinal bleeding -- Risk factors, Nonsteroidal anti-inflammatory drugs -- Evaluation, Nonsteroidal anti-inflammatory drugs -- Physiological aspects, Antiarthritic agents -- Physiological aspects, Antiarthritic agents -- Evaluation
Abstract

SAN FRANCISCO -- Serious lower GI complications occurred 54% less frequently with rofecoxib than with naproxen in a randomized trial involving more than 8,000 rheumatoid arthritis patients. Although it is [...]

Published
2002

3. COX-2 inhibitors: the next generation of non-steroidal anti-inflammatory drugs

Author

Schachna, Lionel and Ryan, Peter F.J.

Subjects
Arthritis -- Drug therapy, Nonsteroidal anti-inflammatory drugs -- Evaluation, Rofecoxib -- Evaluation, Health
Abstract

COX-2 inhibitors represent the next generation of non-steroidal anti-inflammatory agents in the treatment of joint and muscle conditions. Pharmacokinetical action and benefits of COX-2 inhibitors are described.

Published
1999

4. Which is most effective for osteoarthritis of the knee: rofecoxib, celecoxib, or acetaminophen? (Patient-Oriented Evidence that Matters)

Author

Saseen, Joseph J.

Subjects
Osteoarthritis -- Drug therapy, Rofecoxib -- Evaluation, Celecoxib -- Evaluation, Acetaminophen -- Evaluation, Nonsteroidal anti-inflammatory drugs -- Evaluation, COX-2 inhibitors -- Evaluation
Abstract

Geba GP, Weaver AL, Polls AB, Dixon ME, Schnitzer TJ, et al. Efficacy of rofecoxib, celecoxib, and acetaminophen in osteoarthritis of the knee. A randomized trial. JAMA 2002; 287:64-71. * [...]

Published
2002

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