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Start Over Author "Michaelson IA" Topic norepinephrine
7 results on '"Michaelson IA"'

1. Uptake and metabolism of d,1-norepinephrine-7H3 in tissues of immunosympathectomized mice and rats.

Author

Sjöqvist F, Titus E, Michaelson IA, and Taylor P Jr

Subjects
Animals, Colon metabolism, Female, Intestinal Mucosa metabolism, Male, Mice, Microscopy, Electron, Rats, Spleen metabolism, Subcellular Fractions metabolism, Submandibular Gland metabolism, Tritium, Uterus metabolism, Vas Deferens metabolism, Ganglia, Autonomic physiology, Growth Substances pharmacology, Immune Sera, Myocardium metabolism, Norepinephrine metabolism
Published
1965
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2. Uptake and metabolism of dl-norepinephrine by subcellular particles of rat heart.

Author

Michaelson IA, Taylor PW Jr, Richardson KC, and Titus E

Subjects
Animals, Centrifugation, Density Gradient, Chromatography, Paper, Cold Temperature, Glycolates biosynthesis, In Vitro Techniques, Male, Mice, Microscopy, Electron, Monoamine Oxidase metabolism, Pargyline pharmacology, Rats, Sucrose, Tritium, Microsomes metabolism, Myocardium metabolism, Norepinephrine metabolism
Published
1968

3. THE SUBCELLULAR LOCALIZATION OF DOPAMINE AND ACETYLCHOLINE IN THE DOG CAUDATE NUCLEUS.

Author

LAVERTY R, MICHAELSON IA, SHARMAN DF, and WHITTAKER VP

Subjects
Dogs, Acetylcholine, Caudate Nucleus, Chemistry Techniques, Analytical, Dopamine, Electrons, Hypothalamus, Indoles, L-Lactate Dehydrogenase, Microscopy, Microscopy, Electron, Nerve Endings, Norepinephrine, Research, Serotonin, Subcellular Fractions
Abstract

The distribution of dopamine (3,4-dihydroxyphenylethylamine) between the subcellular fractions from homogenates of dog caudate nucleus was compared with the distributions of acetylcholine, 5-hydroxytryptamine and lactate dehydrogenase activity. The distributions of noradrenaline and 5-hydroxytryptamine between the subcellular fractions from homogenates of dog hypothalamus were also determined. Most of the dopamine, in contrast to acetylcholine, occurred in the soluble supernatant fraction; the remainder was associated with the fractions rich in pinched-off nerve ending particles, but localization in any one fraction was not as sharp as that of acetylcholine. Evidence is presented that suggests that the dopamine occurs in a free or easily released form throughout cell cytoplasm.

Published
1963
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