1. [Disorders of physiological parameters of the body (lipid peroxidation and microcirculation) after naso-orbital injuries and the methods of their correction].
- Author
-
Bezshapochnyĭ SB, Loburets VV, Biblina IM, and Pocherniaeva VF
- Subjects
- Adult, Aged, Cerebrovascular Circulation drug effects, Cerebrovascular Disorders drug therapy, Free Radicals adverse effects, Humans, Lipid Peroxidation drug effects, Microcirculation drug effects, Microcirculation physiology, Middle Aged, Multiple Trauma complications, Antioxidants therapeutic use, Cerebrovascular Circulation physiology, Cerebrovascular Disorders etiology, Lipid Peroxidation physiology, Multiple Trauma physiopathology, Nose injuries, Orbit injuries
- Abstract
A naso-orbital injury is often associated with a craniocerebral injury due to the close anatomical localization of the facial and cerebral compartments of the skull. Patients with such injuries showed enhancement of free-radical lipid oxidation and microcirculation disorders. They were controlled by traditional therapeutic methods in combination with antioxidants of direct and indirect action (ascorbic acid, flacumin, alpha-tocopherol acetate, pentoxifylline ) that were given in standard doses. Improvement of microcirculation and decrease of free-radical oxidation of lipids were followed by faster normalization of bioelectric activity and hemodynamics of the brain and earlier clinical recovery. Microcirculation parameters recorded during biomicroscopy of vessels of the bulbar conjunctiva can be used for evaluating cerebral circulation because vessel responses of the eyeball and the brain are similar.
- Published
- 1991