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1. A paper-based chemiluminescence device for the determination of ofloxacin.

Author

Liu W, Guo Y, Li H, Zhao M, Lai Z, and Li B

Subjects
Equipment Design, Limit of Detection, Luminescence, Anti-Bacterial Agents analysis, Luminescent Measurements instrumentation, Ofloxacin analysis, Ophthalmic Solutions chemistry, Paper
Abstract

Paper-based devices are biodegradable and have been used in diagnosis and environmental analysis field. In this work, a wax-printed paper-based analytical device combined with silver nanoparticles (AgNPs) catalyzed luminol chemiluminescence (CL) system for the determination of ofloxacin (OFLX) was presented. It was based on the enhancement of CL intensity of luminol-H2O2-OFLX system by AgNPs. Wax-printing fabrication technique was used to make the simple circle shaped paper device and large scale chips can be fabricated at the same time. Under the selected experimental conditions, a linear relationship was obtained between the CL intensity and the concentration of OFLX in the range from 1.0×10(-9) g/mL to 1.0×10(-6) g/mL with a detection limit of 3.0×10(-10) g/mL. This method has been successfully applied to the determination of OFLX in eyedrop samples., (Copyright © 2014 Elsevier B.V. All rights reserved.)

Published
2015
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2. A paper-based chemiluminescence device for the determination of ofloxacin

Author

Mei Zhao, Baoxin Li, Huifang Li, Zesheng Lai, Wei Liu, and Yumei Guo

Subjects
Paper, Ofloxacin, Luminescence, Analytical chemistry, Silver nanoparticle, Analytical Chemistry, law.invention, Luminol, Luminol chemiluminescence, chemistry.chemical_compound, law, Limit of Detection, medicine, Instrumentation, Spectroscopy, Chemiluminescence, Detection limit, Paper based, Equipment Design, Atomic and Molecular Physics, and Optics, Anti-Bacterial Agents, Linear relationship, chemistry, Luminescent Measurements, Ophthalmic Solutions, medicine.drug
Abstract

Paper-based devices are biodegradable and have been used in diagnosis and environmental analysis field. In this work, a wax-printed paper-based analytical device combined with silver nanoparticles (AgNPs) catalyzed luminol chemiluminescence (CL) system for the determination of ofloxacin (OFLX) was presented. It was based on the enhancement of CL intensity of luminol–H 2 O 2 –OFLX system by AgNPs. Wax-printing fabrication technique was used to make the simple circle shaped paper device and large scale chips can be fabricated at the same time. Under the selected experimental conditions, a linear relationship was obtained between the CL intensity and the concentration of OFLX in the range from 1.0 × 10 − 9 g/mL to 1.0 × 10 − 6 g/mL with a detection limit of 3.0 × 10 − 10 g/mL. This method has been successfully applied to the determination of OFLX in eyedrop samples.

Published
2014