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Motivation: Modern automated laboratories need substantial data management solutions to both store and make accessible the details of the experiments they perform. To be useful, a modern Laboratory Information Management System (LIMS) should be flexible and easily extensible to support evolving laboratory requirements, and should be based on the solid foundations of a robust, well-designed database. We have developed such a database schema to support an automated laboratory that performs experiments in systems biology and high-throughput screening.Results: We describe the design of the database schema (AutoLabDB), detailing the main features and describing why we believe it will be relevant to LIMS manufacturers or custom builders. This database has been developed to support two large automated Robot Scientist systems over the last 5 years, where it has been used as the basis of an LIMS that helps to manage both the laboratory and all the experiment data produced.Availability and implementation: The database schema has been made available as open source (BSD license), so that others may use, extend and improve it to meet their own needs. Example software interfaces to the database are also provided. http://autolabdb.sourceforge.net/Contact: afc@aber.ac.uk [ABSTRACT FROM PUBLISHER]

Promoting replication of models is unarguably a positive step for agent based modelling, as replication promotes rigorous testing. Model replication remains rare, yet is vital to assessing the repeatability of existing agent based models. Notably, more work is needed to assess cross platform and language replication, which represent potential sources of variability between model results. An existing, complex agent based model was replicated using two widely used platforms (NetLogo and Repast). When results generated by the models were compared, the findings differed not only in magnitude but the trends produced by the data, resulting in different conclusions being drawn from each set of model predictions. The variation between the models is believed to be a result of the complexity of encoding a substantial theoretical model in particular programming languages. This highlights the express need to document replication of existing models in order to fully understand the potential limitations to replication. [ABSTRACT FROM AUTHOR]