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Background and Objectives: Buprenorphine/naloxone has been shown to be effective in the treatment of opioid use disorder. Due to its pharmacological properties, induction can be challenging, time-consuming, and result in sudden onset of withdrawal symptoms.Methods: Retrospective case series (n = 2).Results: Two patients with opioid use disorder were successfully started on buprenorphine/naloxone using a rapid micro-induction technique that did not cause precipitated withdrawal or require preceding cessation of other opioids.Discussion and Conclusions: These cases provide an alternative method for starting buprenorphine/naloxone that offers unique benefits compared to protocols previously described in the literature.Scientific Significance: This method can be used to minimize barriers to opioid agonist therapy. (Am J Addict 2019;28:262-265). [ABSTRACT FROM AUTHOR]

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