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Following the April 16, 2020 release of the Opening Up America Again guidelines for relaxing coronavirus disease 2019 (COVID- 19) social distancing policies, local leaders are concerned about future pandemic waves and lack robust strategies for tracking and suppressing transmission. Here, we present a strategy for triggering short-term shelter-in-place orders when hospital admissions surpass a threshold. We use stochastic optimization to derive triggers that ensure hospital surges will not exceed local capacity and lockdowns are as short as possible. For example, Austin, Texas— the fastest-growing large city in the United States—has adopted a COVID-19 response strategy based on this method. Assuming that the relaxation of social distancing increases the risk of infection sixfold, the optimal strategy will trigger a total of 135 d (90% prediction interval: 126 d to 141 d) of sheltering, allow schools to open in the fall, and result in an expected 2,929 deaths (90% prediction interval: 2,837 to 3,026) by September 2021, which is 29% of the annual mortality rate. In the months ahead, policy makers are likely to face difficult choices, and the extent of public restraint and cocooning of vulnerable populations may save or cost thousands of lives. [ABSTRACT FROM AUTHOR]

Vaccines are arguably the most important means of pandemic influenza mitigation. However, as during the 2009 H1N1 pandemic, mass immunization with an effective vaccine may not begin until a pandemic is well underway. In the U.S., state-level public health agencies are responsible for quickly and fairly allocating vaccines as they become available to populations prioritized to receive vaccines. Allocation decisions can be ethically and logistically complex, given several vaccine types in limited and uncertain supply and given competing priority groups with distinct risk profiles and vaccine acceptabilities. We introduce a model for optimizing statewide allocation of multiple vaccine types to multiple priority groups, maximizing equal access. We assume a large fraction of available vaccines are distributed to healthcare providers based on their requests, and then optimize county-level allocation of the remaining doses to achieve equity. We have applied the model to the state of Texas, and incorporated it in a Web-based decision-support tool for the Texas Department of State Health Services (DSHS). Based on vaccine quantities delivered to registered healthcare providers in response to their requests during the 2009 H1N1 pandemic, we find that a relatively small cache of discretionary doses (DSHS reserved 6.8% in 2009) suffices to achieve equity across all counties in Texas. [ABSTRACT FROM AUTHOR]

The construction industry in the United States and other parts of the world has been facing several challenges, including a shortage of skilled workers. A review of the relevant body of knowledge indicates that one of the key reasons for this problem is the absence of human resource management strategies for construction workers at project, corporate, regional, or industry levels. This paper addresses the issues of workforce training and allocation on construction projects. It presents a framework to optimize the investment in, and to make the best use of, the available workforce with the intent to reduce project costs and improve schedule performance. A linear program model, entitled the Optimal Workforce Investment Model, is built to provide an optimization-based framework for matching supply and demand of construction labor most efficiently through training, recruitment, and allocation. Given a project schedule or demand profile and the available pool of workers, the suggested model provides human resource managers a combined strategy for training the available workers and hiring additional workers. The input data to the proposed model consists of a certain available labor pool, cost figures for training workers in different skills, the cost of hiring workers, hourly labor wages, and estimates of affinities between the different considered skills. The objective of the model is to minimize labor costs while satisfying project labor demands. Results from application of the model to typical situations are presented, and recommendations for future developments are made. [ABSTRACT FROM AUTHOR]