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Your search keyword '"R. G. Visser"' showing total 5 results
Start Over Author "R. G. Visser" Topic organic chemistry
5 results on '"R. G. Visser"'

1. Addition of dithio esters and trithiocarbonates to 1-(diethylamino)propyne. Formation of α, β-unsaturated thioamides and vinylogous thioamides

Author

H. J. T. Bos, R. G. Visser, and V. H. M. Elferink

Subjects
chemistry.chemical_compound, Reaction mechanism, Chemistry, Organic chemistry, General Chemistry, Propyne, Tautomer, Medicinal chemistry, Adduct
Abstract

α,β-Unsaturated thioamides and vinylogous thioamides have been prepared by thermal addition of trithiocarbonates RS-C(S)SR1 to 1-(diethylamino)propyne. Aromatic dithio esters Ar-C(S)SR only gave the α,β-unsaturated thioamides. The dithio ester Me2CH-C(S)SMe adds as acidic enethiol tautomer Me2CC(SH)SMe to 1-(diethylamino)propyne. Reaction mechanisms and the stereochemistry of the adducts are discussed.

Published
2010
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2. An improved synthesis of 1,2,3-butatrienyl ethers

Author

R. G. Visser, H. J. T. Bos, and Lambert Brandsma

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, Ketone, chemistry, Organic chemistry, Ether, General Chemistry, Aldehyde
Abstract

A modified synthetic route to 1,2,3-butatrienyl ethers 3 is presented. It involves hydroxyalkylation of 2-propynyl ethers with an aldehyde or a ketone, followed by trimethylsilylation of the hydroxy ether 1 and 1,4-elimination of Me3SiOH from 2 with ethyllithium.

Published
2010
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3. ChemInform Abstract: AN IMPROVED SYNTHESIS OF 1,2,3-BUTATRIENYL ETHERS

Author

Lambert Brandsma, H. J. T. Bos, and R. G. Visser

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, Ketone, chemistry, Organic chemistry, Ether, General Medicine, Aldehyde
Abstract

A modified synthetic route to 1,2,3-butatrienyl ethers 3 is presented. It involves hydroxyalkylation of 2-propynyl ethers with an aldehyde or a ketone, followed by trimethylsilylation of the hydroxy ether 1 and 1,4-elimination of Me3SiOH from 2 with ethyllithium.

Published
1981
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4. An Efficient One-Pot Procedure for Methyl Ethers Derived from Tertiary Acetylenic Alcohols; Strong Influence of Lithium Bromide upon the Coupling between Propynyllithium and Cyclopentanone or Cyclohexanone

Author

S. Mommers, Hermann D. Verkruijsse, P.E. Van Rijn, Lambert Brandsma, and R. G. Visser

Subjects
Coupling (electronics), chemistry.chemical_compound, Chemistry, Lithium bromide, Organic Chemistry, Organic chemistry, Cyclohexanone, Cyclopentanone, Catalysis
Published
1981
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5. An efficient method for the trimethylsilylation of tertiary alcohols

Author

R. G. Visser, Lambert Brandsma, and H. J. T. Bos

Subjects
Hexamethylphosphoric Triamide, chemistry.chemical_compound, Trimethylsilyl chloride, chemistry, Dimethyl sulfoxide, Imidazole, Organic chemistry, General Chemistry, Tertiary alcohols, Triethylamine, Catalysis
Abstract

Tertiary acetylenic alcohols have been transformed into the O-trimethylsilyl derivatives with trimethylsilyl chloride and triethylamine, using catalytic amounts of dimethyl sulfoxide, hexamethylphosphoric triamide, imidazole, or 1,5-diazabicyclo[5.4.0]undec-5-ene. Saturated tertiary alcohols can be trimethylsilylated in the same way.

Published
1980
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