1. 类器官在子宫内膜及其相关疾病研究中的应用.
- Author
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张小蕾, 邓丹妮, 高燕, and 张惠民
- Abstract
Organoids are three-dimensional cellular models cultured in vitro that retain the histological, physiological, and genetic characteristics of original tissues in vivo. They have the advantages of short culture time and high proliferative efficiency. In recent years, organoids have been widely applied in the field of life sciences, particularly in the endometrial research. By overcoming the limitations of conventional cell and animal models, organoids provide a more accurate simulation of the cyclic physiological changes of the endometrium and the characteristics of embryo implantation. Additionally, they show significant potential in disease modeling, precision medicine, drug screening for endometrium -related diseases such as endometriosis, endometrial tumors, and infertility. This review summarizes the progress in the application of organoids in translational research of basic endometrial and related diseases. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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