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Aims: This study aimed to assess the effect of G-CEM, a fluoride-releasing cement, on the development of white spot lesions (WSLs) and their severity around orthodontic brackets., Methods and Materials: This case-control study was conducted by reviewing 140 dental records of fixed orthodontic patients presenting to an orthodontic clinic. The patients were assigned to two groups ( n = 70). In group 1, Transbond XT resin cement, and in group 2, G-CEM had been used for bracket bonding. The frequency and severity of WSLs in each group were evaluated by assessing the available post-treatment photographs of patients and notes left by their orthodontist in their records in this regard. The number of teeth with WSLs in each patient was recorded, and the severity of lesions was categorised by Gorelick's analysis., Statistical Analysis: Comparisons were made using independent t -test, Wilcoxon test and Mann-Whitney test (alpha = 0.05)., Results: In both the maxilla and mandible, the prevalence of WSLs was significantly higher in the Transbond XT group than in the G-CEM group ( P = 0.01). The difference in frequency of WSLs between the maxilla and mandible was not significant within each group ( P > 0.05). Tooth #22 had the highest frequency of WSLs (11.4%) in the Transbond XT group, while teeth #12 and #36 had the highest frequency of WSLs (2.9%) in the G-CEM group. The difference in frequency of WSLs was not significant between males and females ( P > 0.05)., Conclusion: Bracket bonding with G-CEM fluoride-releasing cement significantly reduced the development of WSLs around orthodontic brackets., (Copyright © 2024 Copyright: © 2024 Indian Journal of Dental Research.)

Objective: This study aimed to evaluate the efficacy of "Embrace WetBond", a fluoride-releasing self-adhesive resin cement in preventing the development of white spot lesions (WSLs) during orthodontic treatment.Methods: This retrospective cross-sectional study was conducted on the dental records of 140 patients treated with fixed orthodontic appliances in a private orthodontic clinic in Tehran, Iran. Patients were divided into two equal groups based on the type of adhesive used for bonding orthodontic attachments: Group 1 (control), Transbond XT and Group 2, Embrace wetBond. The prevalence and severity of WSLs were assessed in all teeth from the first molar to the first molar of both jaws using post-treatment photographs. The data were analyzed by chi-square and Mann-Whitney U test and a P-value0.05). The highest prevalence of WSLs was in maxillary lateral incisors (21.4%) and mandibular first molars (15.7%) in the Transbond XT group and maxillary lateral incisors (7.1%) in the WetBond group.Conclusions: The findings of this study suggest that Embrace WetBond adhesive may effectively reduce the risk of WSL development in patients treated with fixed orthodontic appliances. This fluoride-releasing self-adhesive resin cement can be considered a suitable alternative to traditional cement in orthodontic practice.